6.7 animal extracellular matrix Flashcards
main ingredient of the ECM
gylcoproteins
mostly collagen
collagen
forms strong fibers outside the cells
collagen fibers are in a network of woven
proteoglycans
proteoglycans
has small core protein with lots of carbohydrate chains covlaently attached
some cells are attached to the EC< by other ECM glycoproteins like
fibronectin
-attaches the ECM to integrins in the plasma membrane
fibronectin
-attaches the ECM to integrins in the plans membrane
a protein that binds to receptor proteins called integrins
scientist found that the ECM can influences
the activity of genes in the nucleus
regulate a cell’s behavior
-ECM communicates wit ha cell through integrins
integrins
proteins going across cell membrane
- bind to ECM outside
- bind to cytoskeleton inside
- integrate changes occurring inside and outside the cell