6.1.1 patterns of inheritance Flashcards
monohybrid inheritance
genetic cross with alleles at 1 locus
e.g. Tt x Tt
dihybrid inheritance
2 genes inherited on unlinked chromosomes so 2 characteristics at the same time
e.g. RrTt
why is each gamete equally as likely in dihybrid inheritance
independent assortment
ratio for heterozygous dihybrid cross
9:3:3:1
codominance
1 gene with multiple alleles that are both expressed
sex linkage
genes located on sex chromosomes
sex determining genes carried on non-homologous region
why are males more likely to present sex linked genes
XY only needs 1 copy of recessive allele to show characteristic, XX needs both
chi squared test
= sum of ((observed-expected)^2/expected)
degrees of freedom = no. of categories -1
less than critical value - no sig diff = accept null hypothesis
autosomal linkage
more than 1 gene on same non-sex chromosome so inherited together
causes recombinant phenotypes
what exactly causes recombinant phenotypes
crossing over in prophase 1 when bivalents form
epistasis
multiple alleles controlling phenotype, expression of one gene affects another
dominant epistasis
dominant allele masks other gene - only one copy of dom allele needed
what is the heterozygous cross ratio for dominant epistasis
12:3:1
recessive epistasis
recessive allele masks other gene - 2 copies of rec needed
what is the heterozygous cross ratio needed for recessive epistasis
9:3:4