6.1: functional somatic symptoms Flashcards
- Functional Somatic Symptoms (FSS):
Symptoms that are medically unexplained and lack identifiable structural, biochemical, or pathological causes.
o Includes conditions like:
Irritable Bowel Syndrome (IBS)
Chronic Fatigue Syndrome (CFS)
Fibromyalgia
Non-cardiac chest pain
Tension headaches
. Misunderstandings About FSS
- Common Misconceptions:
o FSS symptoms are not real and purely psychological.
o Patients are malingering, seeking attention, or exaggerating symptoms. - Reality:
o Symptoms are genuine, often disabling, and involve a combination of physiological, psychological, and environmental factors.
o Central sensitisation and altered pain processing provide biological explanations for FSS.
o Psychological factors (e.g., stress, hypervigilance) amplify symptom perception but are not sole causes.
- Impact of Misunderstanding:
o Delayed diagnosis: Over-testing to rule out biomedical causes.
o Patient frustration: Repeated referrals without a clear treatment plan.
o Healthcare burden: Unnecessary investigations and consultations
biopsychosocial model FSS
biological factors
- central sensitisation (more sensititve CNS to normal stimuli)
- dysregulation stress response- activity HPA axis
- neurochemical imbalance- decreased seretonin
psychological factors
- hypervigilance - overly aware of sensations
- negative affectivity- anxiety, depression, neuroticism increase symptom sensation
- maladaptive coping
- cognitive misattribution
social:
- cultural normsw- some cultures normalise FSS more than others
- gender- women report more FSS
Neurobiological Model FSS
central sensitisation
- overactive CNS lowers pain threshold - spinal cord changes
- dysrefulation brain network- DMN hyperactivity increases self-referential thoughts ab symptoms,
- HPA axis - chronic stress alter pain pathway and fatigue responses
Cognitive Perceptual Models
- Selective Attention:
o Patients focus excessively on bodily sensations, amplifying benign symptoms.
o Attention is driven by anxiety, emotional distress, and prior illness experiences.
- Common-Sense Model of Illness (Leventhal):
o Patients construct mental models of their symptoms based on:
Identity: Labelling the illness (e.g., “I have IBS”).
Cause: Attributing symptoms to stress or external factors.
Consequences: Predicting how symptoms affect their life.
Timeline: Whether the symptoms are acute, chronic, or cyclical.
Control: Perceptions about treatment efficacy.
Treatment FSS
Principles of treatment
- Focus on a biopsychosocial approach to address all contributing factors.
- Build a strong therapeutic alliance with patients:
o Validate the reality of their symptoms.
o Emphasise a non-judgmental understanding. - Reduce unnecessary medical tests and procedures
Treatment FSS
psychological interventions
-
Cognitive-Behavioural Therapy (CBT):
o Targets maladaptive thought patterns and behaviours.
o Techniques include:
Cognitive Restructuring: Identifying and challenging catastrophic thinking.
Behavioural Activation: Increasing activity levels to break avoidance cycles.
Stress Management: Relaxation, breathing exercises, and problem-solving strategies.
o Effectiveness:
Proven to reduce symptom severity in IBS, CFS, and chronic pain.
-
Mindfulness-Based Stress Reduction (MBSR):
o Encourages present-moment awareness to reduce rumination about symptoms.
o Reduces emotional distress and improves quality of life. -
Acceptance and Commitment Therapy (ACT):
o Focuses on acceptance of symptoms and commitment to valued activities despite discomfort.
treatment FSS
Physical Intervention
- Graded Exercise Therapy (GET):
o Structured, gradual increases in physical activity.
o Prevents deconditioning and improves energy levels.
o Note: Controversial for CFS; pacing strategies are often preferred. - Physiotherapy:
o Useful for pain syndromes like fibromyalgia.
o Involves gentle stretching, aerobic exercise, and posture correction
Treatment FSS
Pharmacological Interventions
- Antidepressants:
o SSRIs (e.g., fluoxetine) and SNRIs (e.g., duloxetine) are effective for comorbid depression and pain modulation.
o Low-dose tricyclic antidepressants (e.g., amitriptyline) reduce pain sensitivity. - Analgesics:
o Opioids are avoided due to the risk of dependency and hyperalgesia.
o Non-opioid analgesics like pregabalin are preferred
Treatment FSS
educational and self-management
- Psychoeducation:
o Educating patients on the biopsychosocial model reduces fear and catastrophic thinking. - Self-Management Programmes:
o Action plans to identify triggers, pace activities, and implement coping strategies.
conclusion FSS
Functional somatic symptoms result from a complex interplay of biological, psychological, and social factors.
Explanatory models such as central sensitisation, cognitive misattribution, and the biopsychosocial model provide frameworks for understanding these symptoms.
Treatment requires a multimodal approach including CBT, mindfulness, physical therapies, and pharmacological interventions, tailored to validate patient experiences and improve functional outcomes.