6-SSS tumorleri Flashcards

1
Q

en sık spinal Tm

A

ependimoma

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2
Q

Astrositoma , IDH mutant Grade2 lezyonları

A

belirli sınır yok infiltratif

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3
Q

Astrositoma , IDH mutant Grade2 seluler ve nukleer atipi?

A

orta derce seluler hafif nukleer atipi

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4
Q

Astrositoma , IDH mutant Grade2 hangi lobları tutar

A

supratentorial
temporal
frontal

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5
Q

Astrositoma , IDH mutant Grade3 lezyonlar

A

çevre parankime infiltratif

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6
Q

Astrositoma , IDH mutant Grade3 selularite ve nukleer atipi?

A

artmışş selularite ve belirgin nukleer atipi

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7
Q

Astrositoma , IDH mutant Grade 2 ve 3 mitotik aktivite

A

grade 2 cok az yok
grade 3 var arttmış

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8
Q

Astrositoma , IDH mutant Grade3 nereyi tutar

A

cerebral hemisferler

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9
Q

Astrositoma , IDH mutant Grade4 belirleyici bulgu

A

kanama ve nekroz odakları

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10
Q

Astrositoma , IDH mutant Grade4 de Tm hucreleri enreye gider ne yapar

A

nekroz odağı etrafında dizilirler (psödopalizadlanma)

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11
Q

CDKN2A/B homozygus delesyon nerde

A

Astrositoma , IDH mutant Grade4

Oligodendroglioma, IDH-mutant,
1p/19q-codeleted Grade4 (bazen)

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12
Q

Oligodendroglioma, IDH-mutant,
1p/19q-codeleted Grade2 Tm hucrelerinin gorunumu

A

monomorfik uniform
yuvarlak nuc ve HALO
dusuk mitoz
KALSIFIKASYON beklenir
mikrokalsifikiye

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13
Q

Oligodendroglioma, IDH-mutant,
1p/19q-codeleted Grade3 Grade2den farkı

A

mitotik aktivite yüksek
nekroz görülebilir
bazen CDKN2A/B delesyonu

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14
Q

Glioblastoma, IDH-wild tip radyoloji görünümü ve gradei

A

hep grade4
radyolojide peritümöral halka görülür

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15
Q

en sık prim beyin Tm

A

Glioblastoma, IDH-wild tip

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16
Q

Glioblastoma, IDH-wild tip 4 tane belirleyicisi

A

microvascular proliferation
necrosis
TERT promoter mutation
EGFR gene amplification
+7/−10 chromosome copy number changes.

17
Q

pilositik astrositom makroskopik kist görünümü

A

grade1 benign
kistik mural nodul

18
Q

pilositik astrositom mikroskobik görünen yapı

A

Rosental fibriller
de içerebilen kompakt ve gevşek
alanlar yapan bipolar hücreler.