6. Nerve structure Flashcards

1
Q

Where do neurones receive impulses

A

dendrites and cell body (perikaryon)

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2
Q

what is a perikaryon

A

cell body surrounded by cytoplasm

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3
Q

where do neurones send impulses through

A

axons

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4
Q

specialised contact sites between nerve cells

A

synapse

terminal boutons of axons are in close contact to target cell

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5
Q

how do neurones adapt

A

strengthening or weakening synpases
altering branching
allows us to learn and memorise

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6
Q

what is between the terminal bouton of an axon and target cell

A

synaptic cleft

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7
Q

what is stored in terminal boutons

A

vesicles containing NTs

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8
Q

what happens at the post synaptic side

A

they have ion channels that open when NTs are bound to binding site
creates a mini current

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9
Q

synaptic transmission is

A

unidirectional and highly specific

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10
Q

synaptic junction in EM

A

electron dense layer on postsynaptic side

mitochondria provide ATP for vesicle recycling and NT synth

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11
Q

afferent

A

neurone impulses along dendrite towards cell body

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12
Q

efferent

A

neurones convey impulses away from cell body

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13
Q

shapes of neurones

A

multipolar
bipolar
pseudo- unipolar (simple reflex- max speed)
very large SA:V

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14
Q

Nissl bodies

A

dark dots in cytoplasm
aggregation of RER towards dendrite
- maintain large membrane area

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15
Q

Why is the nucleus in nerve much larger than nuclei of surrounding nuclei but contain same amount of DNA?

A

a lot more space required for RNA processing

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16
Q

transport system of neurones

A

rails: microtubuli and neurofilaments
vehicles: kinesis and dynein
axoplasmic flow

17
Q

oligodendrites

A
make myelin (40-50 sheaths) 
(myelin have saltatory conduction)
18
Q

myelin sheath

A

are eletrical insulators

formed by oligodendrites or schwann cells in PNS

19
Q

Glial cells

A

astrocytes
cover all surfaces of neurone that are not occupied by synapses or myelin
touch other glial cells, capillaries and neurones
take up nutrients from capillaries and provide to neurones
form BBB and seal on CNS surface
capable of mitosis: brain tumours usually glial origin
no cytoplasm

20
Q

function of glial cells

A

support neuronal architecture
aid in repair
support in functioning/ metabolism
defence

21
Q

Microglia cells

A

immune system of CNS
release cytokines if they detect infectious agents or dead cells
phagocytose and act as local APC
maintain and remodel CNS (eliminate under used synpases)

22
Q

PNS peripheral nerve

A

nerve fibre bundles: small nerves, one fasicle Epineurium: dense collagenous tissue holds large nerves together- several fascicles

23
Q

CNS: efferent neurones

A

perikarya in CNS, axons in PNS

24
Q

CNS: afferent neurones

A

cell bodies and dendrites in PNS

axons in CNS

25
Q

gangla

A

clusters of PNS perikarya

26
Q

clusters of CNS cell bodies

A

nuclei

27
Q

grey matter

A

clusters of neurones (perikarya and some glial)

28
Q

white matter

A

nerve connections (axons and dendrites), mostly myelinised

29
Q

PNS:Perineurium:

A

sheath with flat cells of epithelial character with collagen fibres between them. bundles axons into fasicles

30
Q

PNS: endoneurium

A

loose connective tissue between axon/ dendrite within a fasicle

31
Q

satellite (glial) cells

A

support cells for PNS ganglia

32
Q

PNS: anatomical nerves

A

bundles of nerve extensions (axons, dendrites), held together by epineurium, perineurium and endoneurium

33
Q

PNS: Functional nerve cells in vertebrates

A

are always fully covered by contacts to other neurons or glial cells. They cannot exist without them.

34
Q

schwann cells PNS

A

create one myelin sheath per cell

or wraps itself around unmyelinated nerve extensions