6. Clinical Micro NAT Flashcards
1
Q
What can upregulate the expression of mecA/mecC?
A
When SSCmec-containing bacteria is exposed to B-lactam antibiotics
2
Q
Peptide cross-linking enzymatic domain of PBP2
A
Transpeptidase
3
Q
What do B-lactam antibiotics bind to (mechanism of action)?
A
PBP2 transpeptidase domain = inactivates bacterial wall cross-linking during growth