6: Blood Products and Transfusions Flashcards

1
Q

Below what Hb is transfusion indicated?

A

7g/dl

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2
Q

Below what Hb is transfusion required?

A

5g/dl

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3
Q

Which patients should all be transfused?

A

Symptomatic

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4
Q

Which species compensates well for low Hb?

A

Cats

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5
Q

What are some other indications for transfusion?

A

Thrombocytopaenia, hypoproteinaemia, coagulopathies

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6
Q

Do you get heart murmurs in anaemia or hypovolaemia?

A

Anaemia only

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7
Q

Why can you not freeze RBCs?

A

They have metabolic activity

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8
Q

What does a cryoprecipitate contain?

A

Factor VIII, fibrinogen, vWF

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9
Q

What does cryosupernatant contain?

A

Albumin and vitamin K

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10
Q

Which species is the pet blood bank for?

A

Dogs only

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11
Q

How quickly can the pet blood bank get blood?

A

A few hours

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12
Q

What are the seven types of blood product you can get?

A

Whole blood, plasma, packed RBC, platelet rich, cryoprecipitate, cryosupernatant, leucocyte concentrate

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13
Q

How big must dog donors be?

A

Over 25kg

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14
Q

What are greyhounds good for getting?

A

Good for RBCs, less good for plasma

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15
Q

What blood type should donor dogs be?

A

DEA 1 and 7 negative

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16
Q

How much blood can you take from a donor dog?

A

20ml/kg every 4 weeks (20% volume)

17
Q

What must nutrition be like in a donor dog?

A

High plane

18
Q

How much blood can you take from a donor cat?

A

10% and must monitor for hypovolaemia

19
Q

What must you do before taking a blood donation from a cat?

20
Q

What do you use to find cat blood types?

A

Typing cards

21
Q

How much blood do you take from a cat?

A

43ml in 7ml anticoagulant

22
Q

How long can you store RBCs/whole blood for?

23
Q

What happens to blood if it is stored for too long?

A

Decreased pH (lactic acidosis), decreased DPG so increased Hb/O activity, Ca chelated by citrate, increased ammonia, increased K, decreased Na

24
Q

What can you premedicate with before a blood transfusion?

25
Why do you need a filter on a transfusion set?
To avoid microclots
26
What are the signs of an acute transfusion reaction?
Pyrexia, tachycardia, vomiting, urticaria, diarrhoea, restlessness, haemoglobinuria
27
How do you treat a transfusion reaction?
Stop infusion, steroids, diuretics, diphenhydramine
28
What are some other complications of tranfusions?
Allergies to plasma proteins, volume overload, bacterial contamination, hypoCa, coagulopathies
29
What drug can stop excessive bleeding?
Tranexamic acid
30
Which drug causes platelet release?
Vincristine
31
What drug causes vWF release?
DDAVP
32
What are colloids good for?
Volume support
33
How much isotonic saline do you need to give?
Large amounts