Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Catch Up > 6/5 > Flashcards

6/5 Flashcards

1
Q

DNA Pol 3

A

Main DNA polymerase in procaryotes

  • Synthesizes leading and lagging strand in 5’ to 3’ direction
  • Has 3’-5’ proofreading capabilities and expnuclease activity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

DNA Pol1

A

-After primer has been synthesized has 5’-3’ exonuclease activity that replaces RNA primer with DNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

DNA pol2

A

-Sythesizes over defects during stationary phase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

DNAase

A

GAS allows spread and puss formatons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

LPS

A

outer membrane then space, then peptidoglycan then periplasmic space then membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Tata and CAAT

A

Promotors that bind transcriptin factors and allow for transcription to procede
-Transcripton factors allow for RNA pol binding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

RNA Pols

A

I is for rRNA
II is for mRNA
III is for tRNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Insulins

A
  • Detmir and glargine are long
  • NPH is middle
  • Regular is short
  • Rest are ultrashort: Lispro, aspart
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Glitazones

A
  • Sensitize tissues to insulin by activating PPAR gamma

- Can cause heart failure and hepatotox

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Exenatide and tides

A

-Are GLP-1 analogs that increase secreion of insulin post meal and inhibit glucagon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Sitapliptin

A

DPP4 prevent the degredation of GLP-1 and increae insulin post meal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Fructose metabolism

A
  • Fructokinase phosphorylates nd traps fructse
  • Aldolase B cleaves to ente glycolysis at DHAP and glyceraldehyde
  • Defect in fructokinase is benign and causes fructosuria
  • Defect in aldolase B is severe and causes jaundice and hepatitis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Non latose fermentors

A

Motile are salmonella dna proteus, make H2S

-Nonmotile are shigella and yernsinia, don’t make H2S

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

DNA viruses

A

Most are naked except

  • Herpes (Nuclear membrane)
  • Hep B (hepadenomvirus)
  • Pox (Complex lipid envelope)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

RNA VIruses

A
  • Most are enveloped except
  • Picorno
  • Reo (Rota) (DS)
  • Calici (norwalk)
  • Hepe (Hep E)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Operons

A

Liniear regulation

  • Promotor is upstream of operon which can bind repressor and shut off transcription
  • Promotor binds activators that increase transcription
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Polycistronic RNA

A

-Bacteria make polycistronic RNA which code for multiple genes in a given metabolic circumstance that are controlled by a single operator

18
Q

Proprionyl Co

A
  • Metabolism of threonine, methionine, BCAA and odd chain FA leads to formation of proprionyl CoA
  • Carboxylated using biotin to methyl malonyl CoA
  • B12 converts to succinyl to enter TCA
  • These AA can give off glucose (not leucine)
19
Q

Median Nerve

A
  • Controls motions of
  • Passes medially to the bicepital aponeurosis and brachial artery but latareal to ulnar
  • Can be compressed by pronator teres (medial epicondyle)
  • Compression between flexor digitorum superficialis and profundus muscles
  • Runs between palmaris longus and flexor superficial before getting to flexor retinaculum
  • Recurrent goes to brevises and opponens
  • Longuses done by medial in forearm
  • Senation to first three and half digits on palmar side
20
Q

Ulnar Nerve

A

Runs along the medial acpect of the arm, medial epicondyle

  • Muscles that are ular flexors and half of digitorum profundus
  • All pads and daps, including adductor of thumumb
  • Compression above profundus and below ulnaris
  • Hook of hamate
  • Sensation to last 1 and half digits on palmar and dorsal side
21
Q

Radial Nerve

A

Extensors

  • Can be compressed in axilla
  • Sensation on dorsal aspct of medial fingers, but not fingertips
  • Can be compressed by supinator or brachiordialis/radial disloacation
22
Q

Ureter Blood Supply

A

Upper 1/3 from renal artery
Middle 1/3 from common illiac
lower 1/3 from superior vesicle

23
Q

Ureter

A

Lies in the same ligament in femals and the uterine, vaginal, and inferoir vesicular artery
-But is inferior and posterior, water under the bridge

24
Q

Entacapone

A

COMT inhibitor that works primarily in the periphery

25
Q

Farbers

A

Ceramidase

-Cuteanous neurons and granulomas in the skin

26
Q

Fabrays

A

Galactosidase

27
Q

Candida

A

Enopthalmolitis

28
Q

Carbemazapine

A

-Trigeminal neuralgia first line

29
Q

Gabapentin

A
  • Peripheral Neuropathy
  • Migranes
  • bipolar
  • Postherpetic neuraligia
30
Q

Valproate

A

Myoclonic siezures

31
Q

Benzos

A

Siezures of eclampsia second line to Mg Sulfate

32
Q

Gp120/41

A

product of env

  • Gp120 binds and gp 41 allows for entry
  • GP120 binds to CD 4 and gp 41 binds to coreceptors
33
Q

Dermatomyositis

A

Perifasicular is dermatomyositis and endomysial is polymyositis

34
Q

Medication causing muscle fiber atrophy

A

Cortisone

35
Q

Psoriasis

A

TH1 mediated inflammation

-IFN gamma, IL-12, IL-1

36
Q

ALL

A

T Cell thymus

-9:22 poor prognosis and 12:21 better

37
Q

CML

A

Metamelyocytes and no blasts, low ALP

-AML has blasts

38
Q

Actinic Keratosis

A

eythematous, rough scaly plaques that turn into squamous cell carcionma
-Basal cell is nests of cells that are pearly and flesh colored telangectasias and ulcerations with nests of cells

39
Q

DM CN3

A

DM causes only somatic loss while maintnenace of PANS. Is caused by ischemic injury. If there is presevation of PANS and loss of smoatic 3 think of ischemic injury DM
-Compression is loss of both, anyeurism, hernia

40
Q

Diptheria TOxin

A

E2F, causes cardiotoxicifty and peripheral neropathy if it gets into circulation

41
Q

Familial Hypocaluric Hypercalcemia

A

Defect in Ca sensing proteins that leads to increase rlease of PTH, levels are notmally slightly elevate, not grossly.

  • Minimal long term sequlae
  • Looks similar t thiazide overdose, except the PTH level is high than normal/not supressed by high serum Ca

Catch Up (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions