5.Homeosis and atavism Flashcards

1
Q

Homeosis

A

Transformation of one body segment into another due to changes in homeotic gene function.

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2
Q

Atavism

A

Recapitulation/reappereance
of ancestral traits due to mutations or developmental errors

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3
Q

Bicoid (BCD) protein

A

A maternal morphogen forming an anterior gradient that will regulate gene expression to determine head development in Drosophila.

protein-morphogen_—–gradient like the SHH

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4
Q

Hunchback (hb) gene

A

A gap gene regulated by Bicoid, responsible for early segmentation and forming a boundary between head-thorax

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5
Q

Homeobox

A

A conserved 180 bp of DNA sequence in homeotic genes encoding a DNA-binding domain/homeodomain.

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6
Q

Homeodomain

A

A protein domain encoded by the homeobox, enabling transcription factors to bind specific DNA sequences.

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7
Q

Knock-out mouse

A

A genetically modified mouse with a specific gene inactivated to study the function of the gene through resulting phenotypes.

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8
Q

Segment identity genes

A

Homeotic genes that determine the specific identity of body segments, such as Antennapedia and Bithorax.

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9
Q

Gill arches

A

Embryonic structures in vertebrates that develop into pharyngeal or middle ear components, regulated by homeotic genes.

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10
Q

Electroporation

A

A method to introduce DNA into cells by applying an electric field to create temporary membrane pores.

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