3.Genes and dorsal cell fate Flashcards

1
Q

Egg Polarity Genes

A

Genes that establish the dorsal-ventral and anterior-posterior axes during egg development, such as gurken and torpedo.

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2
Q

Gurken Gene

A

A Drosophila gene encoding the GRK protein, which signals via the TORPEDO receptor to establish dorsal follicle cell identity.

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3
Q

Torpedo Gene

A

Encodes the Epidermal Growth Factor Receptor (EGFR) in Drosophila, important for specifying cell fate via signal transduction

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4
Q

Complementation Test

A

A genetic method to determine if two mutations affect the same gene or different genes based on their ability to restore a wild-type phenotype.

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5
Q

Chimera

A

An organism composed of cells derived from different zygotes, used experimentally to study gene function.

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6
Q

i got this

Signal Transduction Cascade

A

A series of molecular interactions initiated by ligand-receptor binding, resulting in cellular responses.

e.g between glatze protein- toll receptor

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7
Q

Oncogene

A

A mutated proto-oncogene that promotes uncontrolled cell division and tumor formation.

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8
Q

Tumor Suppressor Genes

A

Genes that inhibit cell division; loss of their function can lead to cancer.

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9
Q

Proto-Oncogene

A

A normal gene that facilitates cell proliferation but can become an oncogene through mutation.

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10
Q

FLT3 Gene

A

A proto-oncogene whose mutations are implicated in acute myelogenous leukemia, leading to unregulated cell division.

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