5.4 Hormonal Communication Flashcards
What are endocrine glands?
Specialised group of cells to secrete hormones directly into blood without a duct
What are hormones?
Chemical messengers secreted by endocrine glands, and can be steroid or non-steroid.
What are target cells?
Cells that have specific receptors for a hormone that the hormone needs to act on.
What can stimulate a gland to secrete a hormone?
A change in conc of another chemical, or action potentials.
What happens after a non-steroid hormone binds to a receptor on the cell surface membrane?
A G protein activates an enzyme in the cell surface membrane.
What is the first messenger?
The non-steroid hormone because it carries a chemical message from an endocrine gland to the target cell receptor.
What is the second messenger?
The signalling molecule, because it carries the chemical message from the receptor to the other parts of the cell.
What does the 2nd messenger do?
They activate an enzyme cascade in the cell.
What is a target cell for adrenaline?
Hepatocyte
What enzyme catalyses the reaction of ATP > cAMP ?
Adenylyl cyclase
What does a G protein do?
Activate a membrane bound enzyme after a hormone has bound to a receptor.
What type of gland is the adrenal gland?
Endocrine
What is the outer part of the adrenal gland called?
Cortex
What is the inner part of the adrenal gland called?
Medulla
What type of hormones does the adrenal cortex secrete?
Steroid hormones
Why can steroid hormones directly affect DNA and protein synthesis?
They can diffuse through the lipid bilayer into the cell and nucleus.