5.3 Drugs Flashcards
What is Bethanechol (urecholine?
Direct-acting cholinomimetic
What is Cevimeline (exovac)?
Direct-acting cholinomimetic
What is nicotine?
Direct-acting cholinomimetic
What is pilocarpine (isopto carpine)?
Direct-acting cholinomimetic
What is varenicline (chantix)?
Direct-acting cholinomimetic
What is donezepil (aricept)?
AChE Inhibitor
What is galantamine (Reminyl, Razadyne)?
AChE Inhibitor
What is Pyridostigmine (Mestinon, Regonol) ?
AChE Inhibitor
What is Rivastigmine (Exelon)?
AChE inhibitor
What is a parasympatholytic?
Muscarinic antagonist
What are the naturally occurring parasympatholytics?
Belladonna/deadly nightshade (atropine)
What class of drug is scopolamine? What is it used for?
parasympatholytic
Motion sickness
From Hyoscyamus Niger plant
What class is Propantheline? use?
Antimuscarinic
peptic ulcer
What class is Glycopyrrolate ? Use?
Antimuscarinic
Neuromuscular reversal
What class is Tropicamide? Use?
Antimuscarinic
Dilation of pupil for eye exam
What class is Dicyclomine (Bentyl®)? Use?
Anti-muscarinic
IBS
What class is Tiotropium? Use?
Anti-muscarinic
COPD
What class is Benztropine (Cogentin®)? Use?
Anti-muscarinic
Parkinsons, extrapyramidal symptoms, dystonic rxn
What are: Oxybutinin, Trospium, Darifenacin, Solifenacin, Tolterodine, and Fesoterodine used for? Receptor?
Over active bladder. M3
What are the signs of antimuscarinic toxicity?
Dry mouth Mydriasis Tachycardia Hot flush skin Agitation Delirium – may last up to 1 week
What are the risks for pts with Glaucoma, BPH, or PUD and antimuscarinic drugs?
Glaucoma – esp. angle-closure – dangerously incr IOP
BPH (benign prostatic hyperplasia) – urinary retention
PUD (peptic ulcer diseases) – slow gastric emptying
