5.3 Drugs Flashcards

1
Q

What is Bethanechol (urecholine?

A

Direct-acting cholinomimetic

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2
Q

What is Cevimeline (exovac)?

A

Direct-acting cholinomimetic

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3
Q

What is nicotine?

A

Direct-acting cholinomimetic

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4
Q

What is pilocarpine (isopto carpine)?

A

Direct-acting cholinomimetic

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5
Q

What is varenicline (chantix)?

A

Direct-acting cholinomimetic

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6
Q

What is donezepil (aricept)?

A

AChE Inhibitor

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7
Q

What is galantamine (Reminyl, Razadyne)?

A

AChE Inhibitor

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8
Q

What is Pyridostigmine (Mestinon, Regonol) ?

A

AChE Inhibitor

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9
Q

What is Rivastigmine (Exelon)?

A

AChE inhibitor

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10
Q

What is a parasympatholytic?

A

Muscarinic antagonist

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11
Q

What are the naturally occurring parasympatholytics?

A

Belladonna/deadly nightshade (atropine)

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12
Q

What class of drug is scopolamine? What is it used for?

A

parasympatholytic
Motion sickness
From Hyoscyamus Niger plant

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13
Q

What class is Propantheline? use?

A

Antimuscarinic

peptic ulcer

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14
Q

What class is Glycopyrrolate ? Use?

A

Antimuscarinic

Neuromuscular reversal

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15
Q

What class is Tropicamide? Use?

A

Antimuscarinic

Dilation of pupil for eye exam

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16
Q

What class is Dicyclomine (Bentyl®)? Use?

A

Anti-muscarinic

IBS

17
Q

What class is Tiotropium? Use?

A

Anti-muscarinic

COPD

18
Q

What class is Benztropine (Cogentin®)? Use?

A

Anti-muscarinic

Parkinsons, extrapyramidal symptoms, dystonic rxn

19
Q

What are: Oxybutinin, Trospium, Darifenacin, Solifenacin, Tolterodine, and Fesoterodine used for? Receptor?

A

Over active bladder. M3

20
Q

What are the signs of antimuscarinic toxicity?

A
Dry mouth
Mydriasis
Tachycardia
Hot flush skin
Agitation
Delirium – may last up to 1 week
21
Q

What are the risks for pts with Glaucoma, BPH, or PUD and antimuscarinic drugs?

A

Glaucoma – esp. angle-closure – dangerously incr IOP
BPH (benign prostatic hyperplasia) – urinary retention
PUD (peptic ulcer diseases) – slow gastric emptying