4.2 Flashcards
What are the cholinergic receptors? What neurotransmitter do they use?
ACh
Nicotinic
Muscarinic
What are the cholinergic receptors? What neurotransmitter do they use?
ACh
Nicotinic
Muscarinic
What are the adrenergic receptors? What neurotransmitter do they use?
Alpha, Beta- NE
Dopamine- Dopamine
Where are M1 receptors found?
CNS neurons
Where are M2 receptors found?
Myocardium
Smooth muscle
Where are M3 receptors found?
Exocrine glands
Where are M4, M5 receptors found?
Not well understood
What is the function of nicotinic receptors?
Depolarization- Na/K
Where are nicotinic receptors found?
Post-ganglionic neurons
Motor end plates in skeletal muscle
Where are Alpha 1 receptors found?
Smooth muscle
Where are alpha 2 receptors found?
Presynaptic adrenergic nerve terminals, smooth muscle
Where are Beta 1 receptors found?
Heart
Where are Beta 2 receptors found?
Smooth muscle- in lungs, in uterus, in GI
What are the fates of ACh?
Bind to receptor
Broken down by AChE
Diffuse away
What are the fates of NE?
Bind to receptor
Diffuse Away
Reuptake
Metabolized by enzymes
