5: Visual loss and blindness Flashcards

(65 cards)

1
Q

What is the major artery supplying the eye?

Which artery in the neck does it stem from?

A

Ophthalmic artery

Internal carotid artery

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2
Q

What are the important branches of the ophthalmic artery which you should know?

A

Central retinal artery (inner 2/3rds of retina)

Posterior ciliary arteries (optic nerve head)

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3
Q

Which structure supplies the other 1/3rd of the retina?

A

Choroid

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4
Q

What vascular problems cause sudden visual loss?

A

Occlusion

Haemorrhage

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5
Q

Which artery supplies the inner 2/3rds of the retina?

A

Central retinal artery

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6
Q

What are the symptoms of central retinal artery occlusion?

A

Sudden profound vision loss

Which is painless

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7
Q

What reflex is disrupted in CRAO?

A

Pupillary light reflex

pupil doesn’t constrict in response to light - relative afferent pupil defect (go back and forth fast enough and the pupil will actually dilate in response to light)

because optic nerve is infarcted

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8
Q

What does the retina look like in a central retinal artery occlusion?

A

Pale

Cherry spot fovea

Arteries either absent or blocked

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9
Q

Central retinal artery occusion is a type of ___.

A

stroke

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10
Q

What causes central retinal artery occlusion?

A

Carotid artery disease

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11
Q

How are central retinal artery occlusions managed?

A

Ocular massage (attempt to convert to branch occlusion)

Manage risk factors

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12
Q

What is amaurosis fugax?

A

Transient central artery occlusion

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13
Q

What are the symptoms of amaurosis fugax?

A

Transient painless visual loss

lasting 5 mins with full recovery

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14
Q

How is amaurosis fugax treated?

A

Aspirin (anti-platelet)

Urgent referral to stroke clinic

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15
Q

What is Virchow’s triad?

A

Endothelial injury

Hypercoagulability

Stasis / turbulent blood flow

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16
Q

What are the symptoms of central retinal vein occlusion?

A

Sudden painless visual loss

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17
Q

CRVO is associated with a raised ___ pressure.

A

intraocular

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18
Q

What are the signs of CRVO on fundoscopy?

A

Haemorrhages - inc. cotton wool spots

Dilated torturous veins

Optic disc and macular swelling

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19
Q

What type of scan is used to pick up macular oedema?

A

OCT scan

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20
Q

How is CRVO treated?

A

Laser treatment

Anti-VEGF injections (VEGF released in response to ischaemia, encourages development of poorly structured blood vessels which haemorrhage)

Address risk factors

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21
Q

What processes drive

a) arterial
b) venous

occlusions of the eye?

A

a) Internal carotid disease

b) Venous stasis

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22
Q

Which arteries supply the optic nerve head?

A

Posterior ciliary arteries

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23
Q

What is occlusion of the posterior ciliary arteries also known as?

A

Ischaemic optic neuropathy

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24
Q

What tends to cause arterial ischaemic optic neuropathy?

A

Giant cell arteritis

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25
What causes **non-arteritic ischaemic optic neuropathy**?
**Atherosclerosis**
26
What does the optic disc look like in ischaemic optic neuropathy?
**Swollen**
27
What is the main symptom of **arteritic** **ischaemic optic neuropathy?**
**Sudden irreversible visual loss**
28
Irreversible blindness is an end-stage symptom of giant cell arteritis. What are the other symptoms?
**Headache** **Jaw claudication** **Scalp tenderness** **Tender, enlarged temporal arteries** **Transient arterial occlusions (amaurosis fugax)** **Malaise** **Raised inflammatory markers**
29
How is giant cell arteritis treated to prevent immediate bilateral blindness?
**High dose oral prednisolone**
30
Where in the eye does bleeding tend to occur?
**Vitreous cavity**
31
What is a bleed into the vitreous cavity called?
**Vitreous haemorrhage**
32
What are the symptoms of **vitreous haemorrhage**?
**Loss of vision** **Floaters**
33
What are signs of vitreous haemorrhage on fundoscopy?
**Loss of red reflex** **Clear haemorrhage**
34
How is vitreous haemorrhage managed?
**Management of underlying disease** **Vitrectomy**
35
What are the symptoms of **retinal detachment**?
**GRADUAL painless loss of vision** **Flashes** **Floaters**
36
What is the commonest cause of blindness in elderly people?
**Age-related macular degeneration (ARMD)**
37
What are the two types of ARMD?
**Wet** (sudden) **Dry** (gradual)
38
What causes **wet ARMD**?
**New blood vessels grow in choroid, causing fluid bulge and scarring**
39
What are the symptoms of **wet ARMD?**
**Rapid CENTRAL vision loss** **Metamorphopsia** - visual distortion
40
How is **wet ARMD** treated?
**Anti-VEGF injections**
41
What is the jist of glaucoma?
**Damage to optic nerve**
42
What are two different types of glaucoma?
**Open-angle** **Closed-angle**
43
Where does aqueous fluid drain?
**Canal of Schlemm** (trabecular meshwork) at **iridocorneal angle**
44
What causes closed-angle glaucoma?
**Blockage of trabecular network by bulging iris causes increased IOP**
45
What are the symptoms of closed angle glaucoma?
**Painful, red eye** **Sudden peripheral visual loss** **Headache, nausea, vomiting**
46
How is closed angle glaucoma treated?
**Lower IOP with drops** - carbonic anhydrase, beta blockers etc. **Laser iridotomy** - trabeculectomy???
47
What are some causes of **gradual visual loss**?
**Cataracts** **Dry ARMD** **Refractive error** **Glaucoma** **Diabetic retinopathy**
48
What are **cataracts**?
**Cloudiness of the lens**
49
Which drugs can induce cataracts?
**Steroids**
50
When would cataracts be managed? How?
**If symptomatic** **Surgical lens implant**
51
**Dry** ARMD causes **(sudden / gradual)** visual loss.
**gradual visual loss**
52
ARMD causes (**central / peripheral**) vision loss.
**central vision loss**
53
What causes dry ARMD?
**Build-up of DRUSEN - waste products below retina** Causes retina to tent away from choroid and become atrophic
54
How is **dry ARMD** treated?
**Supportively** - magnifiers, care etc.
55
What is **refractive error**?
**Eye cannot clearly focus an image**
56
What is **myopia**? Which type of lens is used to treat it?
**Short-sightedness** Light focused TOO EARLY, BEFORE RETINA Treated using **concave** lens **(diverges light)**
57
What is **hypermetropia**? Which type of lens is used to treat it?
**Long-sightedness** Light focused too LATE Treated using **convex lenses**
58
What is **astigmatism?**
**Irregular CORNEAL curvature**
59
What is **presbyopia**?
**Loss of accommodation reflex with aging**
60
What type of glaucoma causes **gradual visual loss** or is **asymptomatic**?
**Open-angle glaucoma**
61
What are the signs of **open-angle glaucoma**?
**Cupped disc** **Visual field defects** but patient may be asymptomatic
62
What is the cup:disc ratio like in glaucoma?
**Too big**
63
Where does visual loss occur first in glaucoma?
**Peripheral first**
64
Do patients with glaucoma have tunnel vision?
**No - they fill in the rest of the image (incorrectly)**
65
How is open-angle glaucoma treated?
**Drops to lower BP** **Laser treatment** **Surgery**