5. The Digestive System Flashcards

1
Q

how long is the GI tract

A

4.5 metres long

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2
Q

what are the 4 basic processes of the digestive system:

A
  1. digestion- breakdown of food
  2. absorption- transport of food into bloodstream
  3. motility- peristaltic activity of muscle propelling food along GI tract
  4. secretion- transport of digestive fluids into GI tract
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3
Q

name the accessory glands of the digestive system

A

pancreas
liver
gall bladder
salivary gland

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4
Q

what are the 5 components of the lumen

A

mucosa, submucosa, muscularis, serosa, nerve plexus

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5
Q

what does the submucosa consist of

A

connective tissue
blood
lymphatic vessels

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6
Q

what does the serosa consist of

A

connective tissue

protective layer

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7
Q

what does exocrine mean

A

secretion of enzymes into a duct directed at a target

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8
Q

what does endocrine mean

A

secretion of hormones into the bloodstream

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9
Q

how often is the mucus membrane replaced in an adult

A

every 5 days

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10
Q

what nervous system stimulates saliva response

A

the autonomic nervous system

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11
Q

what enzymes are found in saliva

A

salivary alpha-amylase and lingual lipase

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12
Q

name 3 other functions of saliva

A

lubrication
antibiotic action (lysozyme)
cleans teeth

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13
Q

what does the oesophagus connect

A

the pharynx to the stomach

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14
Q

how does heartburn occur

A

Backflow of upper and lower esophageal sphincters

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15
Q

what types of muscle are found in the oesophagus

A

upper 1/3 skeletal muscle

lower 2/3 smooth muscle

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16
Q

what is the function of parietal cells

A

secrete hydrochloric acid

17
Q

what is the function of chief cells

A

secrete pepsinogen

18
Q

what is pepsinogen

A

a zymogen of pepsin

19
Q

parietal cells also secrete intrinsic factor, what is this

A

a glycoprotein required for the absorption of vitamin b12 in the ileum

20
Q

what is the function of rennin

A

coagulates milk

21
Q

what are the 4 regions of the stomach

A

fundus
body
antrum
pyloris

22
Q

stomach is lined with gastric pits containing what cells

A

neck cells
chief cells
parietal cells

23
Q

what is the function of neck cells

A

produce mucus, found at the top of the mucus pit

24
Q

what hormone triggers the release of pepsinogen and HCL

25
what nerve is important in rest and digest in the stomach
the vagus nerve
26
how does HCL form
H+ and bicarbonate ions from reaction of CO2 and water --------------------- H+ → transported into the lumen for K+ ions Bicarbonate ions→ exchanged for chloride ions which diffuse into the lumen = HCL accumulation in the lumen
27
what is the function of zymogens
zymogens are enzymes in an inactive form, prevents them from becoming reactive in the cells where they were produced
28
what activates pepsinogen
when it encounters HCL in the stomach
29
what is the difference between an endopeptidase and an exopeptidase
endo= break internal peptide bonds= smaller fragments exo= removes one amino acid at a time from either end of a polypeptide
30
how long is the small intestine
2.5-3 metres
31
what makes up the first 30cm of the small intestine
the duodenum, the jejunum and ileum
32
the duodenum is responsible for digestion. what aids it in its role?
chyme from the stomach enzymes from pancreas bile from the liver and gallbladder
33
what is the function of the Crypts of Lieberkühn
secrete bicarbonate-rich fluid to neutralise chyme from the stomach
34
what 4 structures make up the colon
cecum, rectum, anal canal, appendix
35
what is the function of the colon
principle site of water absorption main site of commensal microflora (digestive bacteria)
36
true or false: | there are crypts of Lieberkühn present in the colon but no villi
true