5. systemische Sklerose Flashcards by Ian Paglione

Q

(SSc)

Einteilung (2)

A

diffuse kutane (Dc)
limitierte kutane (Lc)

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Q

(SSc)

limitierte kutane-: Syndrom

A

CREST-Syndrom

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Q

(SSc)

CREST-Syndrom

A

C: Calcinosis cutis

R: Raynaud-Syndrom

E: Ösophageale Hypomotilität

S: Sklerodaktylie

T: Teleangiektasien

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Q

(SSc)

Manifestationen (2)

A

kutane
extrakutane

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Q

(SSc)

kutane Manifestationen: Lokalisationen (2)

A

Finger
Gesicht

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Q

(SSc)

Sklerodaktylie: Befunde (2)

A

Fingerkruppennekrose
Madonnenfinger

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Q

(SSc)

extrakutane Manifestationen (3)

A

Gastrointestinaltrakt
Lungen
Nieren

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Q

(SSc)

Befund im Gesicht

A

Tabaksbeutelmund

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Q

(SSc)

Manifestationen im Gastrointestinaltrakt (2)

A

ösophageale oder intestinale Hypomotilität

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Q

(SSc)

Manifestationen in den Lungen (2)

A

Lungenfibrose
pulmonale Hypertonie

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Q

(SSc)

Manifestationen in den Nieren (2)

A

Niereninsuffizienz
aHT

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Q

(SSc)

Labor (2)

A

Serumelektrophorese
Serologie

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Q

(SSc)

Serumelektrophorese: Befund

A

Hypergammaglobulinämie

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Q

(SSc)

positive Serologie bei fast allen Fällen

A

ANA

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Q

(SSc)

ANA

A

antinukleäre AK

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Q

(SSc)

positive Serologie insb. bei LcSSc

A

ACA

Q

(SSc)

ACA

A

antizentromere AK

Q

(SSc)

positive Serologie insb. bei DcSSc

A

Anti-Scl-70

Q

Anti-Scl-70

A

anti-Topoisomerase I

Q

(SSc)

Anti-Scl-70: Prognose

A

schlechtere

Q

(SSc)

Bildgebungen (4)

A

Röntgen der Hände
CT-Thorax
Ösophagusbreischluck
Sonografie

Q

(SSc)

Röntgen der Hände: Befund

A

gelenkenahe Akroosteolysen

Q

(SSc)

weiterführende Diagnostik

A

Biopsie (falls nötig)

Q

(SSc)

Therapie der Wahl

A

Glucocorticoide p.o.