5 - Mitochondria and oxidative phosphorylation

Question 1

What is the name of the folds of in the inner mitochondrial membrane?

Answer 1

cristae

Question 2

Where is the ETC located?

Answer 2

the inner mitochondrial membrane

Question 3

How does the hydride ion from NADH split up?

Answer 3

into 1 proton and 2 electrons
proton goes to solvent surrounding the enzyme coplex
electrons go to etc

Question 4

The pumping of protons into the intermembrane space establishes a gradient, which is know as a ______ gradient

Answer 4

potential or pH (gradient)

Question 5

Each unit in the etc has a _____ affinity for electrons than the previous unit, allowing them to flow in alogical order

Answer 5

higher

Question 6

What does a negative redox potential insinuate?

Answer 6

tendency to donate electrons

Question 7

What does a positive redox potential insinuate?

Answer 7

tendency to accept electrons

Question 8

Each successive membrane complex has a more ____ redox potential than the previous component in the etc

Answer 8

postive

Question 9

What are the 2 parts of ATP synthase and what are the 3 subunits of each part?

Answer 9

F0 (membrane-bound) = a, b and c

F1 (projects into matrix) = α, β and γ

Question 10

Which subunit in ATP synthase is the one that essentially drives the formation of ATP/ADP?

Answer 10

β

Question 11

Where is succinate dehydrogenase located?
What coenzyme is produced form the reaction that it catalyses?
What mobile carrier does it communicate directly with?

Answer 11

attached to the inner face of the inner mitochondrial membrane
produces FADH2
communicates directly with ubiquinone

Question 12

Why is less ATP produced from FADH2?

Answer 12

FADH2 passes electrons directly to ubiquinone (coenzyme Q), so fewer protons are pumped into the inter mitochondrial space