5 - GI: Constipation Flashcards

1
Q

What is Constipation?

A

Abnormally slow movement of feces through colon w/ accumalation

Straining to have stool

Dry / Hard / Small stools

Feelings of Incomplete bowel evacuation

BLOATING

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2
Q

Epidemiology of Constipation

A

WOMEN > men

no difference in age groups

Higher in > 65 y/o

Common in Pregnancy

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3
Q

Etiology of Constipation

A
  • Disease Induced
    • ​Ulcers / Fissures / hemorroids
    • gallbladder disease apppendicitis / ileitis
    • hypothyroidism / diabetic neuropathy / CVA / MS / IBS / DVT
  • Drug Induced
    • OPIATES + more
  • Psychogenic
    • Depression / eating disorders
  • Lifestyle
    • low calorie / carbs / fiber / inadequite fluid intake
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4
Q

Special Populations in Constipation

A
  • Older Adults >65 y/o
    • Physiologic changes / meds / disease
  • Children
    • ​emotions / febrile / dietary changes / POOR EATING habits
  • Women
    • PREGNANCY / HORMONES
    • IBS / slower gut transit times
    • surgery after childbirth
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5
Q

Common Symptoms of Constipation

A
  • ​Decreased Frequency of bowel movements
  • Difficult Passage of HARD stool
  • Anorexia
  • Dull Headache
  • Lassitude (lack of energy / awareness)
  • Lower Back pain
  • Abdominal Distention
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6
Q

EX-ST of Constipation

A
  • SIGNIFICANT abdominal pain / distention / cramping
  • Marked or unexplained flatulence
  • FEVER + N/V
  • Paraplegia / Quadriplegia
  • Changes in bowel habits
  • Bloody / Dark / Tarry stools
    • change in CALIBER o stool
  • ​Symptoms perisiting fo_r_ >2 weeks or recur _over 3 month_s
  • H/o of IBD
  • Daily laxative use
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7
Q

Non-Pharmacologic Treatment

of Constipation

A
  • Regular bowel habits
  • Increase DIETARY INSOLUBLE FIBER
    • Wheat / grains / oats / fruits / veggies
      • 14g/1000kcal
  • Increase WATER intake
  • Avoid constipating foods
  • Regular EXERCISE
  • Stress management
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8
Q
A

Pharmacologic intervention if quicker relief is needed!

  • Bulk forming Laxatives
  • Lubricants / Emollient
  • Stimulants
  • Saline Laxatives
  • Hyperosmotic Laxatives
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9
Q

Bulk-Forming Laxatives

Onset / Use

A

Metamucil / Fibercon

Psyllium / calcium polycarbophil / methylcellulose

Onset is 12-24 hours

Duration of <72 hours

Used for Treatment & Prevention of Constipation

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10
Q

Bulk-Forming Laxatives

ADR / DI / Counseling

Metamucil / Fibercon

A

Cramping / Flatulence

8oz of WATER Per dose!

obstruction if inadequate fluid intake

Tetracyclines

Seperate by 1-2 hours from all medications

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11
Q

Emollient Laxatives

Onset / Use

A

Colace = Docusate

Used for PREVENTION

Avoid STRAINING

surfactant = increase wetting / soften fecal mass

onset is 1-3 days

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12
Q

Emollient Laxatives

ADR / DI / Counseling

Colace / Docusate

A

Abdominal Pain / Diarrhea

MINERAL OIL

1-2 times a day w/ fluids

not for children <6 y/o

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13
Q

Saline Laxatives

Onset / Use

A

Milk of Magnesia

Mag citrate / MgOH2 / Fleet enema

Osmotics

used for TREATMENT / BOWEL PREP

Onset = 30min - 3 hours (orally)

<1 hour (rectally)

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14
Q

Saline Laxatives

ADR / DI / Counseling

Milk of Magnesia

A

N/V/D

Fluid/e- imbalance + Craming

Warfarin / Digoxin / TCA’s / SPS

  • not for pts w/ :*
  • ileostomy / colostomy / dehydration / renal impairment / CHF*
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15
Q

Stimulant Laxatives

Onset / Use

A

Senokot / Dulcolax

Sennosides / biscodyl / castor oil

Stimulate Peristalsis

used for TREATMENT / BOWEL PREP

Onset is 6-12 hours (orally)

15-60 minutes (rectally)

DNU for > 7 days

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16
Q

Stimulant Laxatives

ADR / DI / Counseling

Senokot / Dulcolax

A

DNU > 7 days

commonly abused

Cramping / Loss of normal bowel fxn

Fluid/e- imbalance

castor oil may induce LABOR

17
Q

Hyperosmotic Laxative

Use / Onset

A

Miralax

PEG 3350 / Glycerin

Osmotic / Local irritant Effect (draws water into rectum)

Used for TREATMENT / PREVENTION / BOWEL PREP

Onset for glycerin is 30 min

onset for PEG = 1-3 Days

18
Q

Hyperosmotic Laxative

ADR / DI / Counseling

Miralax

A

Bloating / Cramping

Abdominal discomfort / Flatulance

Caution in renal disease

Glycerin is just Cramping / irritation / burning

19
Q

Glycerin Dose / Drug Type

A

Hyperosmotic Laxative

for constipation

Adult dose = 3g PR

Children < 6 y/o = 1g - 1.5g PR

cramping / irritation / burning

20
Q

Recomended Laxatives for

Acute Treatment

A

Bulk Forming

Metamucil / Fibercon

Hyperosmotic Laxative

Miralax (PEG)

Stimulant

Senokot / Dulcolax (biscodyl)

21
Q

Recommended Laxatives for

CHRONIC treatment

A

Fluids / Dietary Changes / Physical Activity

Bulk Forming

Metamucil / FiberCon

Occational Stimulants

Senokot / Dulcolax

22
Q

Senakot + Senakot S

Dose / Indication

A

Sennosides +/- docusate

Stimulant Laxative +/- Emollient

8.6 mg +/- 50mg docusate

2 tabs (17.2) at bedtime

2nd dose may be given during the day

23
Q

Senakot + Senakot S

CIP / DI

Sennosides +/- Docusate

A

Appendicitis / Ab pain / n/v

Rectal bleeding / Failure to bowel move

DNU >7 days

24
Q

Senakot + Senakot S

ADR / Consult

Sennosides +/- Docusate

A

Electrolyte/fluid deficiency

hypoKALEMIA / loss of protein

Chest pain / Malabsorption

Ask why they need a laxative?

Bowel habits / appearance

RECTAL BLEEDING SEE MD

Try dietary fiber / fluid intake / exercise

25
Q

Dulcolax

Dose / Indication

A

Biscodyl

Stimulant Laxative

5mg Tab / 10mg suppository

2-3 tabs in single dose / day

Results in 8-12 hours if bedtime

6 hours if taken before breakfast

1 suppository = results in 1 hour

26
Q

Dulcolax

CIP / DI

Biscodyl

A

Appendicitis / Ab pain / n/v

Rectal bleeding / Failure to bowel move

DNU >7 days

<6yo

milk or antacids

catharsis of drugs in colon

27
Q

Dulcolax

ADR / Consult

Biscodyl

A

Electrolyte/fluid deficiency

hypoKALEMIA / loss of protein / Malabsorption

DO NOT CRUSH OR CHEW TABLETS

<7 days

Bowel habits / appearance

RECTAL BLEEDING SEE MD

Try dietary fiber / fluid intake / exercise

28
Q

Colace

Dose / Indication

A

Docusate Sodium

Emollient Laxative

50 / 100 / 250 mg, syrup = 60mg/15ml

50-200mg qd

Results in 1-3 days after 1st dose

15 min after microenema

take liqid with milk/fruit juice

29
Q

Colace

CIP / DI

Docusate

A

Rectal bleeding / Failure to bowel move

DNU >7 days

30
Q

Colace

ADR / Consult

Docusate

A

Bitter Taste / Throat irritation

N/V from syrup or liquid

DNU <7 days

Bowel habits / appearance

RECTAL BLEEDING SEE MD

Try dietary fiber / fluid intake / exercise