5. Extravascular and intravascular hemolysis: causes, pathophysisology, Flashcards
1
Q
WHAT ARETHE CAUSES FOR HEMOLYSISI ?
A
generally classified into inherited (coprsular) thalessemia sickle cell anemia hemoglobin c G6P- deficiency
or acquired (extraciorpsular)
infections
autoimmunity
microangiopathies
2
Q
what is the pathophysiology of extravascular hemolysisi ?
A
RBC is destroyed in the spleen or reticluendothelila tissue
= autoimmune hemolytic anemia nd heridtory spherocytosis
3
Q
what is the pathophysiology of intravascular hemolysisi ?
A
degradation of abc inside the red blood cells DIC G6P defiance PK deficny transfusion incompatibilities