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MSK-1 Test 2 > 5. Cartilage > Flashcards

5. Cartilage Flashcards

1
Q

What are the characteristics of the fibrous layer of the perichondrium?

A

Produces Type 1 collagen and elastin

Acts as a transitional zone

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2
Q

What distinguishes one type of cartilage from another?

A

The Extracellular Matrix differs between types

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3
Q

Where do chondrocytes come from?

A

Chondroblasts

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4
Q

What are type B Synoviocytes?

What do they produce?

A

Fibroblast like synovial cells

Produce Hyaluronate and Synovial Fluid

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5
Q

What is the most common form of cartilage throughout the body?

What type of collagen does it use?

A

Hyaline

Type 2 collagen

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6
Q

What two types of cartilages lack a perichondrium?

A

Hyaline Articular Cartilage

Fibrocartilage

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7
Q

What kind of collagen do you find in Fibrocartilage?

A

Type 1 and 2

(predominantly Type 1)

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8
Q

What kind of connective tissue is the perichondrium?

A

Dense irregular connective tissue

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9
Q

What type of collagen is more common in cartilage?

A

Type 2

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10
Q

What are the four zones of articular cartilage from superficial to deep?

A

Superficial -> Intermediate -> Deep -> Calcified

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11
Q

What disease is associated with the reduction of articular cartilage?

A

Osteoarthritis

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12
Q

What is the layer of connective tissue that holds the cartilage in place, and supports the cartilage from breaking?

A

Perichondrium

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13
Q

In which zone of articular cartilage do you see round cells and collagen running perpendicular to the articulating surface?

A

Deep layer

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14
Q

What is the purpose of Fibrocartilage?

A

Withstands compression and shearing forces

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15
Q

Which zone of the articular cartilage has small, flattened cells?

A

The superficial layer

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16
Q

Cartilage lacks supply from what three structures?

A

Nerves

Blood Vessels

Lymphatics

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17
Q

What are type A Synoviocytes?

A

Phagocytic, macrophage like synovial cells

18
Q

Where might you find Elastic cartilage?

A

External Ear

Epiglottis

Auditory tube

19
Q

In which zone of the articular cartilage do collagen fibers take an oblique course?

A

Intermediate zone

20
Q

Where do we see type 1 collagen in cartilage?

A

Fibrocartilage

Outer perichondrium

21
Q

How are the collagen fibers oriented in articular cartilage?

A

Perpendicular to the tissue surface, and in an arc

22
Q

What secretes the cartilage matrix?

A

Chondroblasts

23
Q

What do you call a group of several chondrocytes in close proximity to each other?

A

An Isogenous Group

24
Q

What type of cartilage growth happens in the perichondrium?

A

Appositional Growth

25
Q

What are the characteristics of the chondrogenic layer of the perichondrium?

A

Inner layer

Differentiates into chondroblasts

Secretes type 2 collagen

26
Q

What is Fibrocartilage made of in the most basic sense?

A

Hyaline cartilage and Dense Regular connective tissue

27
Q

Where might you find Fibrocartilage?

A

Intervertebral Discs

Pubic Symphysis

Temporomandibular Joint

28
Q

What is a lacuna of cartilage?

A

A hollow space in the extracellular matrix of cartilage that is where the chondrocyte sits

29
Q

How is repair cartilage different than other types?

What kinds of collagen does it contain?

What other tissue does it stimulate?

A

It is an intermediate between Hyaline and Fibrous Cartilage

Types 1 and 2

Facilitates bone healing - but can cause bone spurs

30
Q

What is the epiphyseal plate made of?

A

Hyaline Cartilage

31
Q

Where might you find Hyaline cartilage?

A

Articular Cartilage of joints

Larynx

Trachea

Ribs

Embryos

32
Q

What makes Fibrocartilage different?

A

It contains Type 1 collagen, and a lot of it.

33
Q

During periods of cartilage growth, where do new cartilage cells come from?

A

The perichondrium

34
Q

What kind of cartilage growth happens inside existing cartilage?

A

Interstitial growth

35
Q

What lines the ends of bones where they meet inside of an articular capsule?

A

Articular Cartilage

(Hyaline Cartilage with no perichondrium)

36
Q

What is the Territorial Matrix?

What molecule is it rich in?

What molecule does it have less of?

A

The more intensely stained portion of cartilage around any given isogenous group.

Rich in Glucosaminoglycans

Less collagen

37
Q

What has a vascular supply, which then allows the cartilage nearby to gain some nutrients?

A

The perichondrium

38
Q

What is elastic cartilage made of?

A

The same stuff as Hyaline Cartilage, plus Elastin.

39
Q

Which zone of articular cartilage stains darker than the others?

A

Calcified Zone

40
Q

What is the Interterritorial Matrix rich in?

What does it have fewer of?

A

Type 2 Collagen

Proteoglycans

MSK-1 Test 2 (18 decks)

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