5. Anxiety Flashcards
What is anxiety? (Anxiety psychobiology)
The feeling of dread of fear
When is the term anxiety usually used? (Anxiety psychobiology)
When there is no reasonable external cause for the feelings
What does the term clinical anxiety refer to? (Anxiety psychobiology)
Pathological interfering with other activities and priorities
What are the 3 main drug based treatments for anxiety? (Anxiety psychobiology)
- Barbiturates mepobromate
- Benzodiazepines
- Selective serotonin reuptake inhibitors
What are barbiturate mepobromates? (Anxiety psychobiology)
- They act in a non-specific way
- Create a dependence
What are benzodiazepines? (Anxiety psychobiology)
- Anxiolytic effect
- Initially thought to not induce dependence, but now is a major factor in their use
What are selective serotonin repute inhibitors? (Anxiety psychobiology)
- Main pharmacological treatment
- Do have a delayed onset of action
When did clinical use of barbiturate mepobromates cease? (Anxiety psychobiology)
1960
What two ways can psychopharmacological treatments be looked at? (Anxiety psychobiology)
- Disease centred model
- Symptom entered model
What does the disease centred model suggest? (Anxiety psychobiology)
The drug restores normal functioning to the brain
What does the symptom model suggest? (Anxiety psychobiology)
Drugs produce specific changes in aspects of mood, motivation and cognition that makes the condition less disabling
What is the most common neurotransmitter in the synapse of a human? (Anxiety psychobiology)
GABA
What does depolarisation lead to in a synapses? (Anxiety psychobiology)
Release of GABA
What does a release of GABA into the synapse do? (Anxiety psychobiology)
Acts on the postsynaptic GABA receptors to then be transported back to the presynaptic terminal by the repute pump
How many subunits is a GABA receptor made up of? (Anxiety psychobiology)
5
