4.5: Co-Transport and absorption of glucose in the Ileum Flashcards
How is the rate of movement across membranes increased
- Presence of Microvilli
2. Increased density of protein channels and carrier proteins
How do microvilli increase the rate of movement across membranes
They are finger-like projections of the cell membrane and provide more surface area for the insertion of carrier proteins
What are constantly digested
Carbohydrates and proteins
What does the constant digestion of carbohydrates and proteins mean
That there is normally a greater concentration of glucose and amino acids within the ileum than in the blood
What does a higher concentration of glucose and amino acids in the ileum than in the blood mean
That there is a concentration gradient down which glucose moves by facilitated diffusion from the inside of the ileum to the blood
What does diffusion only result in
The concentrations either side of the inestinal epithelial becoming equal. Therefore not all glucose/amino acids are abosrbed
Why are most of the glucose/amino acids actually absorbed
Because glucose and amino acids are actively transported - therefore they are both all absorbed into the blood
What is the mechanism by which glucose and amino acids are absorbed from the small intestine
Co-Transport
How are glucose and amino acids absorbed via co-transport
Glucose and amino acids are drawn into the cells along with sodium ions that have been actively transported out by the Na/K pump.
Process of co-transport
- Sodium ions are actively transported out of epithelial cells, by the na/k pump and into the blood
- This maintains a much higher concentration of sodium ions in the lumen of the intestine than the inside of epithelial cells
- Sodium ions diffuse into the epithelial cells down this conc gradient through a co-transport protein in the membrane. As sodium ions diffuse down they carry either amino acids or glucose molecules into the cell with them
- The glucose/amino acids pass into the blood plasma by facilitated diffusion.
Where is ATP used
in the production of a Na concentration gradient (Sodium/Pottasium pump)