4.3 Protein Conformation:Fibrous and Globular

Question 1

how does the back bone fold to give globular proteins

Answer 1

fold back on itself to produce a spherical shape. their helical and pleated sections can be arranged to bring the ends of the sequence close to each other in 3-D

Question 2

differences btwn globular and fibrous

Answer 2

globular are water soluble have compact structures, tertiary and quaternary structures can be complex

Question 3

Which is more imp conservation of structure or aa sequence. Why

Answer 3

Structure because it dictates fn. Sequence alignment of tuna and Rhodopila globiformis have 42% aa identity yet structure is similar