42 - Prevention of Ischemic Stroke

Question 1

non-pharms

Answer 1

• smoking cessation
• weight reduction
• diet/exercise
• recommend rehab therapy within 24-48 hours if there are residual neurologic deficits

Question 2

List 4 options for antiplatelet therapy

Answer 2

• ASA
• Clopidogrel
• Ticlopidine
• Dipyridamole/ASA

Question 3

s/e of ticlopidine

Answer 3

• diarrhea, skin rash, neutropenia so frequent monitoring required and not reoutinely recommended
• clopidogrel is as effective and better tolerated

Question 4

_____ is more effective than ASA

Answer 4

clopidogrel

Question 5

Compare dipyridamole/ASA to ASA alone and clopidogrel alone

Answer 5

• better than ASA alone

- comparable to clopidogrel

Question 6

List 2 vitamin K antagonists

Answer 6

• acenocoumarol

- warfarin

Question 7

vitamin K antagonists are superior to clopidogrel plus ASA for prevention of vascular events in patients with _____ at high risk for stroke

Answer 7

A. fib

Question 8

Which DOACs are approved for prevention of systemic embolism?

Answer 8

• dabigatran (direct thrombin inhibitor)

- apixaban, endoxaban, rivaroxaban (factor Xa inhibitors)

Question 9

What is dabigatran’s reversal agent?

Answer 9

idarucizumab

Question 10

For a noncardiogenic stroke, give ______ agent

Answer 10

antiplatelet

Question 11

For a cardiogenic stroke, give ______ agent

Answer 11

anticoagulant