25 - Restless Legs Syndrome Flashcards
1
Q
RLS responds to ______ therapy
A
dopaminergic
2
Q
What is RLS believed to be caused by?
A
- genetic component
- dysfunctional dopaminergic transmission
- low brain iron stores
3
Q
What is secondary RLS associated with ?
A
DM, ESRD, iron deficiency, MS, PD, pregnancy and venous insufficiency
4
Q
Non-pharms for RLS?
A
- mental alertness activities to reduce symptoms during times of boredom
- abstain from alcohol, caffeine, and nicotine
- hot baths
- stretching, moderate amounts of exercise
- get enough sleep
- d/c meds that may be blocking dopamine (antipsychotics, dopamine blocking anti-emetics and sedating AHs)
5
Q
If _____ deficient, then supplement
A
iron
6
Q
Options for intermittent RLS
A
- levodopa
- BZD
- low dose opioids (codeine)
7
Q
Options for chronic persistent RLS
A
- dopamine agonists
- GABA derivatives
8
Q
Options for pregnancy?
A
None of these drugs are first line for pregnancy
- rule out iron, magnesium or folate deficiency
- non-pharms
- can use opioids if necessary
9
Q
Options for breastfeeding?
A
gaba derivatives and levodopa may be ok
