4.2 ABO Blood Group System Flashcards
Which of the following distinguishes the A1 blood group from the A2 blood group?
An A2 person may form anti-A1; an A1 person will not form anti-A1
A patient’s serum is incompatible with O cells. The patient RBCs give a negative reaction to anti-H lectin. What is the most likely cause of these results?
The patient may be a Bombay phenotype individual
What antibodies are formed by a Bombay phenotype individual?
Anti-A, B, and H
Anti-A, Acquired B antigens have been found in _______
Group A persons
Blood is crossmatched on an A-positive person with a negative antibody screen. The patient received a transfusion of A-positive RBCs 3 years ago. The donors chosen for crossmatching were A-positive. Crossmatching was run on the automated analyzer and yielded 3+ incompatibility. How can these results be explained?
The patient is an A2 with anti-A1
A patient’s RBCs forward as group O, serum agglutinates B cells (4+) only. Your next step would be:
Incubate washed RBCs with anti-A1 and anti-A,B for 30 minutes at room temperature
Which typing results are most likely to occur when a patient has an acquired B antigen?
Anti-A 4+, anti-B 1+, A1 cells neg, B cells 4+
Which blood group has the LEAST amount of H antigen?
A1B
What type RBCs can be transfused to an A2 person with anti-A1?
A or O
What should be done if all forward and reverse ABO results as well as the autocontrol are positive?
Wash the cells with warm saline, and autoadsorb the serum at 4°C
What should be done if all forward and reverse ABO results are negative?
Incubate at 22°C or 4°C to enhance weak expression
N-acetyl-D-galactosamine is the immunodominant carbohydrate that reacts with _____
Dolichos biflorus
A stem cell transplant recipient was retyped when she was transferred from another hospital. What is the most likely cause of the following results?
Immunodeficiency
What reaction would be the same for an A1 and an A2 person?
Positive reaction with anti-A,B
A female patient at 28 weeks’ pregnancy yields the following results:
Which of the following could be causing the ABO discrepancy?
Alloantibody in patient serum
Which condition would most likely be responsible for the following typing results?
Weak or excessive antigen(s)
Which of the following results is most likely discrepant?
Negative A1 cells
A 61-year-old male with a history of multiple myeloma underwent stem cell
transplantation 3 years ago. The donor was O positive, and the recipient was B positive.
The patient is admitted to a community hospital for fatigue and nausea. Typing results
reveal the following:
How would you report this type?
Undetermined
