4.1.1f) The structure, different roles and modes of action of T and B lymphocytes in the specific immune response

Question 1

Killer T cells

Answer 1

Can kill a cell directly
Perforins- perforate
1. Cell leaks out
2. Exocytosis breaks down cell

Question 2

Helper T cells

Answer 2

Secrete interleukins to activate other T & B cells
Activates more macrophages

Question 3

Memory T cells

Answer 3

Remain in lymph nodes to respond rapidly if the same type of pathogen invades again

Question 4

Regulator T cells

Answer 4

Slow down & stop the immune response/reaction after about 1 week
(e.g. Lupus, MS and Type 2 diabetes)

Question 5

B Lymphocytes

Answer 5

Helper T cells releases interleukins to activate B cells (cell signalling)
Matures in bone marrow

Question 6

Clonal selection

Answer 6

Correct antibody selected for cloning

Question 7

Clonal expansion

Answer 7

Clones of plasma & memory cells made by mitosis

Question 8

Plasma B cells

Answer 8

Produce & secrete antibodies into bloodstream- only lives for a few days
Transported by blood & lymph system
Antibody-antigen complex