4.1.1e) The structure and mode of action of phagocytes

Question 1

Phagocytis process

Answer 1

1. Phagocyte attracted by chemicals produced by pathogen
2. Phagocytes recognises pathogens as non-self & binds to it
3. Phagocyte engulfs the pathogen to form phagosome-lysosome moves towards phagosome & combine with it (hydrolysis)
4. Phagocyte combines with lysosome - phagolysosome (hydrolysis)
5. Enzymes from the lysosome digest & destroy the pathogen
   Digested pathogen absorbed by phagocyte- antigens combine with MHC in the cytoplasm
6. MHC/antigen complex is displayed on phagocyte membrane, making an APC