4 - Smoking Cessation Flashcards
1
Q
What are the common consequences of smoking?
A
- Lung cancer
- Oral cancer
- Lowered estrogen levels
- Heart disease
- Periodontal disease
2
Q
How is nicotine used for cessation therapy?
A
- Potent vasoconstrictor
- Pts must completely stop smoking prior to therapy
- Nicotine raises cardiovascular risks - so can’t smoke at the same time
3
Q
What are all products of nicotine replacement therapy designed to do?
A
Decrease cravings for nicotine
4
Q
What drug is a dopamine reuptake inhibitor that is used to cessation therapy?
A
- bupropion (Zyban)
5
Q
When is there a risk for emergent hypertension while taking bupropion?
A
With concurrent patch use
6
Q
What cessation drug is a partial neuronal alpha4 B2 nicotinic receptor agonist that occupies nicotine receptor sites in the brain?
A
varenicline (Chantix)
Results in decreased craving and withdrawal symptoms
7
Q
What are some of the general side effects that have been changed to varenicline (Chantix)?
A
- Suicidal thoughts and erratic/aggressive behavior
- Adverse cardiovascular events
