4-Questions Flashcards
The GALT immunity overlying Peyer’s patches is first facilitated by which cells?
M cells
Which cells involved in the oral tolerance suppress Th1, Th2 and Th17 responses?
Treg cells
Which cells are activated by IgE cross linking with FCeRI in food induced anaphylaxis?
Mast cells
Ingesting peanuts and causing anaphylaxis is inducing the activation of macrophages by what?
IgG
Mucosal remodeling and rillers atrophy from the ingestion of gluten is from what cell type?
Myfibroblasts
What is the main function of Ghrelin in the body?
Stimulate hunger
For patients diagnosed with TII DM, what would you expect of GLP-1?
Decreased
What is the mechanism of action for the drug Orlistat?
Does not allow GI lipase to bind to fat
What is the most common small intestine tumor?
Adenocarcinoma
What is the most common extranodal site for the ileum?
Ileum
What is the name of cell involved in adenocarcinomas in small intestine?
Kulchitsky cells
A genetic disorder in which the ______ absorbs iron too well is known as __________
Duodenum; hemachromatosis
Pt with alcoholic cirrhosis would have AST to ALT ratio of?
2:1
Liver disease characterized by decreased Cu incorporation into ceruloplasmin and decreased Cu secretion into bile?
Wilson’s
Common way to clinically test for Wilson’s disease?
Penicillaminc challenge
Pt with obvious skin color change with hereditary hemochromatosis must have what blood Cu level?
24
What is the definitive diagnosis for hereditary hemochromatosis?
Liver biopsy
Lab results common in Hep A,B,C
ALT>AST
Part of Charcot’s triad?
Fever
Sign of pre hepatic disease?
Increased unconjugated bilirubin
Pt with portal vein thrombosis common?
Ascites
Most likely to develop alcoholic cirrhosis
70 yo with 2 pints of whiskey a day
During necrosis of liver, where is hepatocytes is likely to be affected first?
Zone 1
Home remedy of pruritus due to retention of bile salts
Grapefruit juice