4) Primary Structure and Secondary Structure

Question 1

Primary Structure

The primary structure of a protein is the s_____________ of a___________ a_____________.

P_________ b___________

Answer 1

Sequence
amino acids

peptide bonds

Question 2

Primary Structure

The amino acids have different __ g______.
These groups will have slightly different c_________ which will affect how the protein folds up.

Answer 2

R Groups

charges

Question 3

Secondary Structure

The long chains of amino acids f______ into regions with r__________ p__________.

Answer 3

fold

repeating patterns

Question 4

Secondary Structure

There are two categories of these repeating patterns:

1) A_________ H_______________
2) B_______ P_________ S___________

Answer 4

1) Alpha Helices

2) Beta Pleated Sheets

Question 5

Secondary Structure

P_____________ b____________

                       and

h___________ b_____________

Answer 5

peptide bonds

hydrogen bonds

Question 6

Secondary Structure - Hydrogen Bonds (a)

The a__________ h___________ and b________ p__________ s____________ arise because all of the amino acids, when bonded in a chain contain ________ groups and _________ groups.

The hydrogen found in the -____ group is slightly p____________ and the o_________ found in the -_________ group is slightly n___________.

Answer 6

alpha helices
beta pleated sheets
-C=O
-NH

-NH
Positive
oxygen
-C=O
negative

Question 7

Secondary Structure - Hydrogen Bonds (b)

The slightly p_________ charge of the hydrogen atom and the slightly n________ charge of the oxygen atom results in a h________ bond between a___________ a___________

Answer 7

positive
negative
hydrogen
amino acids

Question 8

Secondary Structure - Hydrogen Bonds (c)

Hydrogen bonds exist between p________ p___________ and p__________ n__________ charges.

Answer 8

partial positive

partial negative charges

Question 9

Secondary Structure - Definition

The secondary structure of a protein is the c_________ or f_____________ of the p__________ c_________ into alpha helices and beta pleated sheets due to the formation of h____________ b_______________.

Answer 9

curling/folding
polypeptide chains
hydrogen bonds