12) Enzymes - Active Sites

Question 1

Enzymes can only catalyse a reaction if the s________ binds to its a________ s_______.

Answer 1

substrate

active site

Question 2

Most metabolic reactions occur in a s_______ of s_______ s__________.

Answer 2

a series of small steps

Question 3

Active sites contain r________ m________ that can carry out these small steps in a c_______ w_____ with a l_________ a___________ e__________.

Answer 3

reactive molecules
controlled way
lower activation energy

Question 4

The active site can have various c_______ g________ and they all interact with the s________ in the right way to perform the correct r__________.

Answer 4

chemical groups
substrate
reactions

Question 5

When a substrate binds to the active site, it is h_______ in a s________ o__________ that facilitates its reaction.

Answer 5

held

specific orientation

Question 6

The activation energy is lowered because the c_______ g_______ in the active site hold the substrate in the best possible o_________ that they can, making the reaction as e_______ as possible.

Answer 6

chemical groups
orientation
easy

Question 7

The active site can also put p_________ p_________ on the substrate, further l_________ the activation energy.

Answer 7

physical pressure

lowering