4. Microfilaments Flashcards
1
Q
Diameter of microfilaments
A
7-9 nm
2
Q
Actin monomer binding proteins
A
Profilin
Thymosin beta
3
Q
Straight filament nucleators
A
formin
Spire
4
Q
Branched filament nucleators
A
Arp2/Arp3 complex
5
Q
Filament capping proteins, plus end
A
CapZ
6
Q
Filament capping proteins, minus end
A
Tropomodulin
7
Q
Filament severing proteins
A
ADF-cofilin
Severin
8
Q
Filament side binding stabilisers
A
Tropomodulin
Nebulin
9
Q
Bundling proteins
A
Fibrin
alpha-actinin
10
Q
Cross-linking proteins
A
Filamin
11
Q
Membrane linkers
A
Spectrin
Dystrophin
12
Q
Motors
A
Myosins
13
Q
Examples of drugs/toxins to study actin
A
Cytochalasin B D Tolytoxin Latrunculin A Phalloidin Botulinum toxin