12. ER - processing and stress response Flashcards
1
Q
What chaperones are involved in protein folding?
A
EDEM
OS9
2
Q
Involved in the ER quality control system (3)
A
SDF-BIP-ERDjSA complex
CNX/CRT cycle
PDI system
3
Q
What does the unfolded protein response trigger?
A
Reduced translation
Enhanced protein folding
Quick removal of unfolded proteins
4
Q
What does IRE1 do in stress signalling?
A
Splices the mRNA of bZIP transcription factors, removing transmembrane domain - causes UPR genes
5
Q
What activates the UPR in plants? 2
A
bZIP 60 and 28
6
Q
What activates the UPR in mammals? 2
A
ATF6, XBP1
7
Q
What recognises bacteria and fungi in plants?
A
Bacteria - FLS2
Fungi - CERK1
