4: Lymphatics Flashcards
3 components of lymph system
- Lymph fluid
- Lymph vessels
- Organized lymph tissues/organs
Lymphatic development in embryo
Begins during week 5, significant presence by week 20
When does lymphoid tissue stop increasing?
Around 6-9 years old
Substances found in lymph fluid
- Substances that leak out of arteries, like proteins and electrolytes
- Immune cells
- Foreign Ags, bacteria, and viruses
- Clotting factors
- Chylomicrons
Four tissues that do not have lymph vessels
- Epidermis
- Endomysium of muscle
- Cartilage
- Bone marrow
Superficial vs deep LNs
Superficial: within subq tissue
Deep: beneath fascia, muscle, and organs
Virchow’s node
Left supraclavicular node -> indicated intrathoracic or abdominal cancer
Epitrochlear nodes
In elbow region, indicate secondary syphilis
Three tonsils and their locations
- Palatine: lateral pharynx
- Lingual: posterior 1/3 of tongue
- Pharyngeal: adenoids at nasopharyngeal border
Normal interstitial fluid pressure (Pif)
-6.3mmHg (negative pressure system
What happens if interstitial fluid pressure reaches above 0 mmHg
Lymph caps collapse and flow ceases -> increased hydrostatic pressure, decreased plasma colloid osmotic pressure, increased cap permeability
What two forces help lymph move through large vessels
- Muscle contractions
2. Breathing
What happens with each breath in terms of lymph movement (2 things)
- Increased negative intrathoracic pressure pulls fluid centrally
- Direct force on cisterna chyli, pushes fluid superiorly
Sympathetics effect on lymph valves
Increased symps -> tighter valves -> decreased lymph flow into venous system
Sympathetics effect on lymph smooth muscle
Increased symps -> decreased peristalsis -> lymph congestion
