4] Infection Control Flashcards
Micro-organisms that survive on the skin
Normal flora
How do normal flora serve a protective function?
By stopping the growth of more virulent micro-organisms
2 ways infections occur
Breach of intact skin or systemic infection
6 ways intact skin gets breached
Microscopic Surgery Trauma Lacerations Burns Pressure ulcers
2 ways for systemic infections
Blood borne
Sepsis
10 factors that influence liklihood of an infection
Necrosis/slough Perfusion Size of wound Duration of wound Smoking Drug and alcohol use Poor nutrition Lack of sleep and exercise Comorbidities Immunosuppression
Presence of bacteria on wound surfaces with no multiplication of bacteria
Contamination
All wounds are ???
Contaminated
Multiplication of micro-organisms on the
wound surface without invasion of wound tissue and no host immune response
Colonization
Presence of proliferating bacteria on the
wound surface where healing is delayed or stopped and subtle clinical signs of host
injury are noted
Critical colonization
Invasion and multiplication of micro-
organisms in wound tissue resulting in
pathophysiologic effects or tissue injury
Infection
7 signs of critical colonization
Discoloration of granulation tissue Friable granulation tissue Pocketing in wound base Wound breakdown Bad odor High serous exudate levels Delayed healing
Acute indicators of infected wounds
Pain Redness Edema Heat Pus
serous drainage with concurrent inflammation,
discoloration of granulation tissue, friable granulation tissue, foul odor, wound
breakdown is what type of wound?
Chronic wound
Diabetic indicator of infected wound
Pus or 2+ signs of inflammation
Surgical site infection indicator
Pus or signs of inflammation and a + culture
What’s an indicator of an infected wound in an immunosuppressed pt?
Pain
Population of community of bacterial living in organized structures at a liquid interface
Biofilm
Biofilm provides ?
Physical protection to bacteria
Biofilm is present in 70-80% of ?
Chronic wounds
Biofilm bacteria is attached to?
Tissue surfaces
Biofilm looks?
Cloudy, slimy
Biofilm interferes with?
Epithelialization
Treatment for biofilm
Debridement or apply nontoxic antiseptic solution daily
What are 4 issues with biofilm?
No validated clinical characteristics
No routine test
Depth for debridement unknown
Inadequate prevention
What’s the acronym for a superficial infection
NERDS
What does NERDS stand for
Non healing wounds Exudate Red and bleeding wound surface granulation tissue Debris (yellow/black) on wound surface Smell (bad odor)
What’s the acronym for deep infection?
STONES
What does STONES stand for?
Size bigger Temperature increased Os (exposed bone) New wound breakdown Exudate, erythema, edema Smell/odor
Superficial wound infection Dx occurs
Within 30 days post op
Superficial wound infection involves skin or subcutaneous tissue of the incision and atleast one of?
Pus
Isolated organisms from culture
Signs/Sx of infection
Dx of SSI by surgeon or attending MD
Wound cultures only need to be obtained when
There are overt or subtle clinical signs of infection
OR
If wound is deteriorating or getting bigger
What’s recommended for all diabetic foot infections
Wound culture
Treatment for infections
Antibiotic for 24 hours or longer
3 major systemic antibiotics
Penicillin
Cephalosporins
Vancomycin
What kind of substances are cytotoxic and should be limited with wound cleansing?
Bleach
Acetic acid (vinegar)
Betadine
Hydrogen peroxide
2 non tox is cleaning solutions
Isotonic saline Wound cleanser (NOT a skin cleanser)
agent that inhibits orkills microorganisms
Antimicrobial
3 classes of antimicrobials
Antiseptic
Antibacterial
Antifungal
agent that destroys or stopsbacterial growth (i.e. Bacitracin)
Antibacterial
substance that prevents or arrests the growth or action of microorganisms
Antiseptic
agent that inhibits or kills fungi
Antifungal
Betadine
Antiseptic
Bacitracin
Antibacterial
Nystatin
Antifungal
Examples: povidine iodine, acetic acid,hydrogen peroxide, dakin’s solution
Examples of antiseptics
H2O2 impairs ?
Microcirculation
Adkins (bleach) delays
Clotting, angiogenesis and epithelialization
Antibacterials should not be used regularly. T or F
True
Examples of antibacterials (6)
Bacitracin Neosporin Gentamicin Metrogel Mupirocin Silvadene
Acticoat, Aquacel Ag, Silvasorb,
Silverlon
All of these products are comparable in ability to fight topical infection.
Dressing?
Ionic silver
Ex] Iodosorb, Iodoflex
Topical dressing?
Molecular iodine
Patients infected or colonized with organisms that can be transmitted by direct or indirect contact
Gowns and gloves must be worn
Contact precautions
Patients known or suspected to be infected with
organisms transmitted by large particle droplets
generated by coughing, sneezing, talking – closeproximity
Droplet precautions
Patients known or suspected to be infected by
small particle residue of evaporated droplets that remain suspended in air and can be dispersed by air currents
Airborne precautions
Infection of dermis and subcutaneous layers
Cellulitis
Forms red, hot painful large areas
Ex] lower legs
Cellulitis
Patients with ? Are prone to anaerobic cellulitis of thr feet
DM
Cellulitis is frequently accompanied by
Infection
Diagnosed by culture, symptoms, ESR, and WBC
Cellulitis
Managing cellulitis includes ?
Antibiotics, elevation of the body part, cool and wet dressing
Healthcare associated MRSA usually
Blood stream infection
Community associated MRSA usually
Skin and soft tissue infection
Manifest as skin infections suchas pimples and boils
Treatment is with vancomycin,
clindamycin, or linezolid
MRSA
What does MRSA stand for
Methicillin-Resistant Staphylococcus Aureus
Another form of highly resistant bacteria normally found in intestines and female genital tract
VRE
What does VRE stand for
(Vancomycin-Resistant Enterococci)
Choice for treating VRE
Vancomycin
Commonly found in soil and water but also found on skin of healthy people
Outbreaks rare outside of healthcare settings
Acinetobacter Infections
Acinetobacter Infections causes
Variety of diseases from pneumonia to serious blood and wound infections
Acinetobacter Infections can colonize, especially in
Trach sites and open wounds
Infection that attacks the deeplayers of fascia
Very aggressive, fast moving
Releases a toxin that quickly
and irreparably destroys flesh and muscle
Necrotizing fasciitis
Surgeons often must remove
skin, large groups of muscle, orentire limbs to save a person’s
life
Necrotizing fasciitis
Yeast, heat rash, candida, whatever – it’s destructive to the skin!
Satellite lesions typically
present
Fungus
Best way to treat fungus
With powder + zinc oxide ointment