1] Evaluation And Intervention Flashcards
8 functions of the skin
Protect from infection Conserve body fluids Temp regulation Excretion Secretion Produce Vit D Appearance Sensation
3 layers of the skin
Epidermis
Dermis
Hypodermis (subcutaneous)
Epidermis has how many layers?
5
What are the 5 layers of the epidermis?
Stratum corneum (outer) Stratum lucidum Stratum granulosum Stratum spinosum Stratum basale (inner)
Outermost layer of the skin
Epidermis
Thickness of eye lids
.05 mm
Thickness of palms/soles
1.5 mm
4 cells in epidermis
Melanocytes
Langerhan cells
Merkel cells
Keratinocytes
Produce melanin, a pigment that contributes to skin color & absorbs UV light to
protect DNA from damage.
Melanocytes
Participate in immune responseby fighting various microbes that invade the skin.
Langerhan cells
Sensory receptor cells that areresponsible for sensation of touch.
Merkel cells
Produce keratin, a tough protectiveprotein that protects skin & creates water repellent
seal.
Keratinocytes
Deepest layer of the epidermis
Stratum basale
Divides continuously
Contains stem cells which continually divide & push
new cells to surface.
Stratum basale
Contains melanocytes and merkel cells
Stratum basale
Thickest layer of the skin
Stratum spinosum
Prickle cells interlock and support skin
S. Spinosum
Involved in transfer of substances in and out of body
S spinosum
Has basal cells and langerhan cells
S spinosum
Which layer initiates keratinization?
S granulosum
How on does keratinization take?
4 weeks
? produce ?, a tough protectiveprotein that makes up the majority of the
structures of the skin, hair, and nails
Keratinocytes
Keratin
What happens as kcytes move through the stratum granulosum and lucidum ?
They enlarge, flatter and adhere together
What happens at the end of keratinization?
Cells fuse together into tough durable material that continues to surface to the skin
Appears only in thethicker areas of the skin, i.e. fingertips, palms, and soles
S lucidum
Comprised of dead keratinocytes &
protects against UVrays.
S lucidum
10-30 layers of continuously shedding dead
keratinocytes which are replaced from below
S corneum
Lipids help seal these dead cells together to form a barrier to keep water out/in.
S corneum
Shedding process is how many days in the young?
26-30
Shredding process is how many days in the elderly?
42-50 days
3 functions of the dermis
Regulate temperature
Give dermis nutrients saturated with blood
Store water
2 layers of the dermis
Papillary
Reticular
Thin arrangement of collagen fibers
Papillary layer of dermis
How is the papillary layer connected to the epidermis?
Via papillae
Sensory touch receptors in the papillary layer
Meissners corpuscle
Contains thick collagen fibers arranged parallel to skin surface
Reticular layer
Reticular layer contains what corpuscles that do?
Pacinian corpuscles that are sensory receptors for deep pressure
What two things in the dermis do you need to help your healing tissue be strong?
Collagen and elastin
Supply nutrients and oxygen to the skin
Takes away cell waste and cell products
Transports vitamin D produced in the skin to the rest of the body
Constricts and dilates to aid with temperature regulation
Functions of blood vessels
Bathes the skin tissues withlymph, a substance that
contains infection-fighting
cells of the immune system
Lymph vessels
Attempt to destroy any
infection or invading
organisms as the lymph
circulates to lymph nodes
Lymph vessels
Average person has approximately 3 million of these
Sweat glands
3 types of sweat glands
Apocrine
Eccrine
Sebaceous
Found only in armpits, areolae of nipples andgenital regions
Apocrine sweat glands
Larger, deeper and produce thicker secretionsthan eccrine glands
Apocrine sweat glands
Become active at puberty
Apocrine sweat glands
Found over the entire body
Collect ducts deep in skin that connect to surface
Eccrine glands
Sweat is a mix of ?
99% water and 1% salt and fats
These glands secrete sweat and regulates body temp
Eccrine glands
Secrete oils that keep skinsupple and smooth,
waterproofs, protects from overgrowth of
bacteria/fungus
Sebaceous sweat glands
Empties via ducts into base of hair follicle
Secretes sebum
Sebaceous glands
What is sebum?
Mixture of fats, waxes and hydrocarbons
Collagen is for ?
Elastin is for?
Durability
Flexibility
Protein is made by
Fibroblasts
Supports epidermis by giving durability
Collagen
Similar protein that keeps skin flexible
Elastin
Nerve endings contain
Pain and touch receptors
Smooth muscle attached to hair follicle
Erector pilli muscles
Has blood vessels, nerves, lymph, hair follicles also cross into this layer
Hypodermis/subcutaneous layer
How do epidermis and dermis heal?
Regeneration
How does everything else besides epidermis and dermis heal?
Repair
What is regeneration
Tissue is replaced with like tissue
What is repair?
Scar formation; tissues repair by “filling in” with scar tissue
What phase is 4 -6 days in normal healing?
Inflammatory phase
How long does normal healing usually take?
2 -4 weeks
Purpose:
Body reacts to the wound and sets the process of healing in motion
Clear away dead cells and bacteria
Inflammatory phase
Hemostasis is?
Inhibiting oxygen of surrounding tissue
What is a vascular response?
Local transient vasoconstriction in response to the injury
What’s released during vascular response?
Platelets, leukocytes, erythrocytes
Vascular response is mediated by ? And prolonged by. ?
Mediated by norepinephrine and prolonged by serotonin
Vasodilation occurs when
Bradykinin and histamine are released from damaged tissue
Begin to digest bacteria and become part of the exudate
Cells consist of neutrophils, eosinophils, and basophils
Polymorphonuclear granulocytes
Give rise to macrophages, lymphocytes and platelets
Mononuclear granulocytes
Main function of macrophages
Phagocytosis
Angiogenesis begins with
Macrophages
4 chemical mediators
Histamine
Serotonin
Kinins
Prostaglandins
Phase is 4/6 to 21 days
Proliferation phase
4 stages of proliferation phase
Re-epithelialization
Fibroblasts
Neovascularization
Contraction
Recreating permeability barrier
Re-epithelialization
Replacement and reinforcement of new tissue (granulation tissue)
Fibroplasia
New blood supply
Neovascularization
Decreasing wound size
Contraction
Migration of epithelial cells across a wound
Basement membrane forms
Re-epithelialization
Dermal fibroblasts change into myofibroblastsand migrate into the wound and makes collagen
Fibroplasia
Process that occurs as the wound closes due to the loss of tissue
Begins approx the 5th day
Contraction
Movement of pre-existing tissue toward thecenter – NOT the formation of new tissue
Contraction
Which phase is 21 days to 2/3 years
Maturation/remodeling phase
Phases of healing
Inflammatory
Proliferation
Maturation/remodeling
Tensile strength will reach about 70-80% of original tissue by week 12
Maturation/remodeling phase
Collagen and elastin form in this phase
Maturation/remodeling phase
What’s a prediction of wound healing?
If the surface area decreases by 39% at 2 weeks- has better chance of healing
If phases of healing and sequence of events occur in an orderly fashion, wounds are
considered
Acute
If wounds fall out of the orderly healing
cascade of events, wounds are considered
Chronic
Acute wounds usually happen as a result of
Trauma or surgery
Abrasions are
Acute
Avulsions are
Acute wounds
Crush wounds
Acute
Burns
Acute
Cuts and lacerations
Acute
Missile wounds
Acute
Punctures
Acute
Caused by tangential shearing of skin by a rough surface
Abrasions
Most commonly caused by road surface during MVA “road rash”
Abrasions
What’s degloving?
Avulsions
Caused when a portion of the skin is
caught on a sharp object while the body is moving away from the object and a flap of skin is removed
Avulsions
Most commonly occurs in industrial
settings with rotary tools or with ejectionsfrom a motor vehicle
Avulsions
Most common injuries are getting
fingers caught in a closing door or feet run over by car.
Crush wound
Occurs when a heavy object falls onto a
portion of a person’s body, splits the skin andmay even shatter or tear underlying
structures.
Crush wounds
sharp pieces of bone penetrate and tear surrounding soft tissue &skin which created an open wound
Open fracture
Most likely to occur with high energy injuries,
more superficial bones, and among the elderly.
Open fracture
Characterized by a
slice wound created by a sharp object
which leaves
straight/even edges
Cuts/incisions
3 basic mechanisms of injury for lacerations
Shearing
Tension
Compression
Shearing
Small amount of force on a small area which typically results in minimal cell injury due to the sharp
instrument
High amount of force at an angle with a blunt object which tears skin with significant tissue damage (i.e.grazing injury)
Tension MOI for laceration
High force at makes direct
perpendicular contact causing jagged/shredded wound edges and severe tissue damage (i.e. punch)
Compression MOI for laceration
High velocity projectiles (3000 ft/sec)
create negative pressure waves known as ? behind the bullet which
causes expansion & collapse of tissue and even further damage.
Cavitation
Deep & narrow wounds created by sharp objects such as nails, knives, or animal
teeth
Puncture wounds
6 types of burns
Flame Scald Contact Electrical Chemical Frostbite
Scald burn
Boiling water or steam
Contact burn
Hot surface like stove or tar
Electrical burn
Live wires or lightning
Chemical burn
Acids, basics or caustic materials
Frostbite burns
Excess cold
Fell off the healing cascade due to prolonged Inflammatory phase
Chronic wounds
Require topical therapies and appropriate supportive therapies
Chronic wounds
4 examples of chronic wounds
Arterial, venous, pressure, neuropathic ulcers
Wound environment consists of what 3 things
Moisture
Necrotic tissue
Wound temperature
Any insult to the wound that may delay orinterrupt healing process
Trauma
What does continuous pressure to a wound do?
Interrupts blood supply and delays healing
Aging process increases which phase and decreases which phase?
Increases inflammatory phase
Decreases maturation phase
Superficial wounds are in the
Epidermis
Partial thickness wounds are in the
Dermis
Full thickness wounds are in the
Hypodermics or muscle, tendon, bone
Stage 1 pressure injuries
Superficial wound
Contusions or bruises
Superficial wounds
Stage 3 pressure injuries
Partial thickness wound
Stage 3 and 4 pressure injuries
Full thickness wounds
Skin tears
Partial thickness
Venous wounds
Partial thickness
Lacerations and abrasions
Partial thickness wounds
Incontinence associated dermatitis
Partial thickness wound
Diabetic and arterial wounds
Full thickness wounds
3 types of wound prognosis
Healable
Maintenance
Palliative
What is healable prognosis?
The cause of the wound can be corrected or compensated with treatment
What is maintenance wound prognosis
Poor treatment adherence or lack of appropriate resources is the barrier to being healed
What is a palliative prognosis
Cause is not treatable
Coexisting medical conditions or drugs do not prevent healing
Healable
Goal of healable?
To promote wound healing
Coexisting medical conditions or drugs that may stall healing
Maintenance wound prognosis
Goal of maintenance wound prognosis
Prevent further deterioration or breakdown
Advocate for them
Promote adherence
Manage pain
Coexisting medical conditions prevent normal healing
Palliative wound prognosis
prevent further skin breakdown,
trauma, and infection; promote comfort; pain management
Goal of palliative wound prognosis