4. Disorders of metabolism Flashcards

1
Q

Isotonic Fluid Loss could be caused by what?

A

Haemorrhage

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2
Q

Hypotonic Fluid loss could be caused by what?

A

Dehydration

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3
Q

An isotonic fluid gain could be caused by what?

A

giving saline solution

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4
Q

ADH is produced by what?

A

Median Eminence –> Hypothalamus

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5
Q

Respiratory Acidosis (CO2 // HCO3)

A

High CO2

High HCO3

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6
Q

If compensatory HCO3 matches ?

A

CO2

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7
Q

Additive Disorder example (acidosis etc)

A

Respiratory Acidosis + Metabolic Acidosis

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8
Q

Lower the pKa, the stronger the?

A

Acid

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9
Q

Higher the Ka, the stronger the?

A

Acid

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10
Q

co2 dissolves to form what?

A

H2CO3

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11
Q

What enzyme is responsible for converting HCO3 to CO2

A

Carbonic Anhydrase

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12
Q

Hb produces what?

A

Production of HCO3

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13
Q

Monohydrogen Phosphate forms a buffer with what?

A

dihydrogen phosphate

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14
Q

Ammonium in the blood is generally found as what?

A

Ammonia form

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15
Q

Albumin has what charge?

A

Negative

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16
Q

A shift to the right in the oxyhaemoglobin dissociation curve leads to what in the affinity for Oxygen

A

Decrease in O2 affinity

more o2 to tissues

17
Q

A shift to the left in the oxyhaemoglobin dissociation curve leads to what in the affinity for Oxygen

A

Increase in O2 affinity

less o2 to tissues

18
Q

How are bicarbonates absorbed in proximal convulated tubule cells?

A

CO2 binds with H20 intracellular

19
Q

At the distal convulated tubule (DCT), H2CO3 dissociates into what?

A

H+

HCO3

20
Q

Aldosterone acts on what part of the kidney

A

DCT

21
Q

Excretion of H+ Ions occurs at what part of the tubules?

A

Distal Tubules

22
Q

Reabsorption of bicarbonates occurs at what part of the tubules?

A

Proximal Tubules

23
Q

Regeneration of bicarbonates occurs at what part of the tubules?

A

Distal Tubules