4. Disorders of metabolism Flashcards
Isotonic Fluid Loss could be caused by what?
Haemorrhage
Hypotonic Fluid loss could be caused by what?
Dehydration
An isotonic fluid gain could be caused by what?
giving saline solution
ADH is produced by what?
Median Eminence –> Hypothalamus
Respiratory Acidosis (CO2 // HCO3)
High CO2
High HCO3
If compensatory HCO3 matches ?
CO2
Additive Disorder example (acidosis etc)
Respiratory Acidosis + Metabolic Acidosis
Lower the pKa, the stronger the?
Acid
Higher the Ka, the stronger the?
Acid
co2 dissolves to form what?
H2CO3
What enzyme is responsible for converting HCO3 to CO2
Carbonic Anhydrase
Hb produces what?
Production of HCO3
Monohydrogen Phosphate forms a buffer with what?
dihydrogen phosphate
Ammonium in the blood is generally found as what?
Ammonia form
Albumin has what charge?
Negative
A shift to the right in the oxyhaemoglobin dissociation curve leads to what in the affinity for Oxygen
Decrease in O2 affinity
more o2 to tissues
A shift to the left in the oxyhaemoglobin dissociation curve leads to what in the affinity for Oxygen
Increase in O2 affinity
less o2 to tissues
How are bicarbonates absorbed in proximal convulated tubule cells?
CO2 binds with H20 intracellular
At the distal convulated tubule (DCT), H2CO3 dissociates into what?
H+
HCO3
Aldosterone acts on what part of the kidney
DCT
Excretion of H+ Ions occurs at what part of the tubules?
Distal Tubules
Reabsorption of bicarbonates occurs at what part of the tubules?
Proximal Tubules
Regeneration of bicarbonates occurs at what part of the tubules?
Distal Tubules
