4: Connective Tissue Flashcards
3 types of CT proper
loose irregular, dense irregular, dense regular
What is amorphous ground substance composed of?
proteoglycans, glycosaminoglycans, and interstitial fluid
What is the major cell of CT proper?
fibroblasts
What are cells found in CT proper?
fibroblasts, plasma cells, eosinophils, macrophages, mast cells, adipose cells
T/F: Fibroblasts can de-differentiate to become other connective tissue cell types
T
Where are mast cells most common?
loose CT in skin and intestine
What are mast cells rich in?
histamine and heparin
Which cells have a wagon wheel or clock appearance?
plasma cells
What is the most common fiber?
collagen type I
Where are collagen type I fibers found?
dermis, fascia, bone, ligaments, and tendons
How are collagen type I fibers organized?
regular or irregular arranged bundles and layers in dense CT
Procollagen
made and secreted by fibroblasts
What does procollagen cross link with?
tropocollagen
What fibers are seen with a silver stain?
reticular fibers
Which fibers look like a fragile lattice?
reticular fibers