(4) chapter 19: Cancer

Question 1

Cancer cell division

Answer 1

-cancer cells grow and divide in an uncontrolled manner, spreading throughout the body and interfering with he function of normal tissues and organs

Question 2

Tumor

Answer 2

-any abnormal proliferation of cells

Question 3

Benign tumor

Answer 3

remain confined to the original location. neither invading surrounding normal tissue nor spreading to distant body sites

Question 4

Malignant tumor

Answer 4

a) can invade surrounding normal tissue
b) can spread throughout the body cia the circulatory or lymphatic systems (metastasis)
- only malignant tumor are referred to as cancers

Question 5

What is most lethal cancer?

Answer 5

lung cancer

Question 6

Carcinomas

Answer 6

malignancies of epithelial cells (about 90% of human cancers)

Question 7

Sarcomas

Answer 7

-solid tumors of connective tissue such as muscle, bone, cartilage, and fibrous tissue (rare in humans)

Question 8

Leukemias & Lymphomas

Answer 8

arise from the blood-forming cells and immune system cells respectively

Question 9

4 most common cancers

Answer 9

1. prostate
2. breast
3. lung
4. colon/rectum

Question 10

Tumor clonality

Answer 10

-tumors develop from single cells that begin to proliferate abnormally

Question 11

SIngle cell origin of cancer

Answer 11

-single-cell origin has been demonstrated by analysis of X chromosome inactivation patterns

Question 12

Development of cancer multistep process

Answer 12

1. Tumor initiation

2. tumor progression

Question 13

Tumore initiation

Answer 13

-mutation leads to abnormal proliferation of a