4. Cancer Epidemiology Flashcards

1
Q

What is epidemiology?

A

A branch of medical science dealing with incidence, distribution and control of disease

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2
Q

What is descriptive epidemiology?

A

Study of distributions (What, when)

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3
Q

What is analytical epidemiology?

A

Study of determinants, why, how

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4
Q

Why should cancer occurrence be studied?

A

Aid research, prioritization of health care

Stimulate hypotheses regarding cause of cancer

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5
Q

What does prevalence refer to?

A

The total number of cases in a population

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6
Q

What does incidence refer to?

A

The number of new cases in a population

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7
Q

What does mortality refer to?

A

Number of deaths in population due to disease

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8
Q

Does prevalence take into account the number of people changing over time?

A

No

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9
Q

How do you calculate crude incidence?

A

Incidence = Number of new cases in year X / Number of persons at risk of the disease during year X * 100 000

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10
Q

What are the most common cancers in Australia?

A
  1. Prostate
  2. Colorectal
  3. Breast
  4. Melanoma
  5. Lung
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11
Q

What are the most common cancers in the age group 0-14?

A
  1. Lymphatic Leukaemia
  2. Brain / Central Nervous System
  3. Lymphomas
  4. Kidney
  5. Connective Tissue
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12
Q

What are the most common cancers in the age group, 15-44?

A
  1. Melanoma
  2. Breast
  3. All lymphoma
  4. Thyroid
  5. Testis
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13
Q

Most common cancers in ages 45-64?

A
  1. Breast
  2. Prostate
  3. Colorectal
  4. Melanoma
  5. Lung
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14
Q

What is the most common cancer in ages 65+?

A
  1. Prostate
  2. Colorectal
  3. Lung
  4. Breast
  5. Melanoma
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15
Q

What are mortality rates affected by?

A

Incidence

Prognosis

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16
Q

What cancer has the highest mortality among men?

A

Lung cancer

17
Q

What cancer has the highest incidence among men?

18
Q

What cancer has the highest mortality rate among women?

A

Lung cancer

19
Q

What cancer has the highest incidence rate among women?

20
Q

What are cancer rates affected by?

A
Genetics
Living/working conditions
Healthcare
   - Prevention
   - Diagnosis
   - Treatment
Registration Systems
21
Q

What do observational studies do?

A

Find associations between risk factors and cancer

Find potential interactions between factors

22
Q

What are some internal risk factors?

A

Genetics

Age

23
Q

What are some external risk factors?is

A
Lifestyle factors
Environmental
Medication
Hormones
Viruses
24
Q

How does a case control study design work?

A

Get two groups, one with cancer one without
Separate both groups into another two groups
One exposed to X and those who werent

25
How does a cohort study design work?
A group, exposed and not exposed, is followed over an amount of time Separated into cancer and non cancer group
26
For accurate association between disease and exposure, one needs to aim for?
Accurate diagnosis of disease | Accurate exposure assesment
27
What is the synergy project?
Case-control studies, looking at effects of exposures to smoking and working environments
28
After smoking, what is the most significant occupational risk factor?
Occupational exposures
29
What is a major risk factor in mining. construction and farming?
Silica exposure