3.8 The Nervous System Flashcards
What is a stimulus ?
A detectable change in the internal or external environment of an organism that produces a response
What is a receptor ?
A specialised structure that detects a specific type of stimulus
What is an effector ?
An organ, tissue or cell that produces a response to a stimulus and carries out the response
What is a response ?
Detects the change causing a stimulus
What is a neurone ?
Specialised cells adapted to rapidly carry nervous impulse from 1 part of the body to another
What is an impulse ?
Pulse of electrical energy sent along the axon
What is the purpose of the nervous system ?
To detect changes or stimuli inside the body and in the environment to process and store information and initiate responses
What are the 2 parts of the nervous system ?
Central and peripheral
What makes up the central nervous system ?
Brain and spinal cord
What is the function of the central nervous system ?
Process information from a stimulus
What does the central nervous system contain ?
Grey matter
White matter
Relay neurones
What is white matter made up of ?
Nerve fibres and myelin
What is grey matter made up of ?
Nerve fibres of relay neurones
Relay and motor neurone cell bodies
What is the 2 parts of the peripheral nervous system ?
Autonomous and somatic
What is the function of the autonomous nervous system ?
Interacts with internal organs and glands providing unconscious control of the functions of internal organs
What is the function of somatic nervous system ?
Interacts with sensory organs and voluntary muscle allowing impulses to be carried from receptors to the central nervous system then to effectors
What neurones does the somatic nervous system contain ?
Sensory and motor
What are the 8 senses ?
Sight
Hearing
Touch
Pain
Smell
Taste
Temperature
Balance
What are the 2 types of stimuli ?
Internal and external
What is an internal stimuli ?
Changes within an organism often signalling alteration in its psychological state
What is an external stimuli ?
Environmental factors influencing an organism externally
What are the 2 sides of a spinal cord called ?
Dorsal and ventral
What is a hydra made up of ?
A simple nervous system called a nerve net
What makes up a neurone network ?
Sensory and ganglia cells
What is the function of ganglion cells ?
Provide connections in several directions
What is the function of sensory cells ?
Detect stimuli
What are the features of a Hydra ?
No brain
Slow conduction speed
Respond to limited number of stimuli due to have very few effectors
What is a reflex ?
An inborn response to a stimulus
What are the features of a reflex ?
Rapid
Automatic
Preventive
Protective
What is a reflex arc ?
A rapid and automatic response resulting from nervous impulses initiated by a stimulus
What are the stages of a reflex arc ?
1) Stimulus
2)Sensory Receptor
3) Sensory Neurone
4) Central Nervous system
5) Motor Neurone
6) Reponse
7) Feedback
What is a neurone ?
Specialised cells adapted to carry nervous impulses from 1 part of the body to another
What are the 3 types of neurones ?
Sensory
Relay
Motor
What is the function of a sensory neurone ?
Carries impulses from sense receptors to the central nervous system
What is the function of a relay neurone ?
Receive impulses from sensory neurone and transmit to motor neurone
What is the function of a motor neurone ?
Carry impulses from the central nervous system to the effector
What is the function of dendrites ?
Receive and carry information to cell body
What is the function of the cell body of a motor neurone ?
Carry out normal cell functions. Contains many lysosomes and mitochondria
What is the function of the nucleus in a motor neurone ?
Control cell function
What is the function of the axon in a motor neurone ?
Carry information from the cell body to the axon endings
What is the function of axon endings in a motor neurone ?
Transmit impulse to another neurone or affector
What is the function of the Nodes of Ranvier in a motor neurone ?
Unmeylinated sections of the neurone, the impulse leaps from 1 node to the other
What is the function of the myelin sheath in a motor neurone ?
Provide electrical insulation to speed up the conduction of an electrical impulse
What is the function of a Schwann cell ?
Forms the myelin sheath
What is a resting potential ?
The action of sodium potassium pumps and potassium ion channels leads to a potential difference across the neurone membrane. No nervous impulse is conducted
What is potential difference ?
Difference in electrical charge between 2 areas
What is an ion ?
Electrically charge particles due to the loss or gain of an electron
What is a cation ?
Positively charged ion
What is an anion ?
Negatively charged ion
What is the definition of polarised ?
Where there is a potential difference across a membrane
What is the definition of depolarised ?
When a cell membrane has a temporary reversal of potential
What is a nervous impulse ?
Transmission of a change in potential along a nerve fibre associated with movement of sodium ions
What is an action potential ?
A rapid rise and fall of electrical potential across a membrane of nerve cell as a nervous impulse passes
What is an excitable cell ?
One in which the potential across a cell can be altered
What is impulse propagation?
An action potential which begins at one end and is propagated along the axon
Which membrane is more negative in resting potential ?
Inside
What is the difference in mV between the inside and outside membrane
Inside is more negative by -70
How are resting potentials maintained ?
Sodium potassium pumps
Voltage gated sodium channels
Large protein anions
What are the 7 stages on an action potential graph ?
Stimulus
Threshold
Depolarisation
Action potential
Depolarisation
Hyperpolarisation
Resting state
Why can’t an impulse travel backwards ?
Due to the absolute refractory period
Voltage gated sodium channels are temporarily inactivated and don’t reopen until new resting potential has been established preventing another action potential
What is threshold potential ?
If the intensity of a stimulus exceeds -55mV threshold an action potential is initiated
What is saltatory conduction ?
The process of an action potential jumping from node to node
What is a localised current ?
Current occurring in 1 part of an axon
What is hyperpolarisation ?
Movement of a cells membrane potential to a more negative value. A hyperpolarised neurone is less likely to fire an action potential
What is a refractory period ?
A period of time after an action potential in which further action potentials are impossible or less likely
What are voltage gated sodium channels ?
A membrane protein channel that is opened at a set voltage
What are the 2 types of refractory periods ?
Absolute and relative
What happens in the absolute refractory period ?
No new action potentials are initiated
Voltage gated sodium channels are inactivated
Lasts around 1ms
What happens in the relative refractory period ?
Occurs during hyperpolarisation
Action potential only occurs is impulse is strong enough
Lasts 4 to 10 ms
What causes the relative refractory period ?
Outward diffusion of potassium ions making the threshold harder to reach
What are the factors that affect the speed of conduction of a nervous impulse ?
Temperature
Axon diameter
Myelination
How does temperature affect speed of conduction of nervous impulses ?
Higher temperatures = Increased kinetic energy =Ions move faster
How does axon diameter affect speed of conduction of nervous impulses ?
Greater the diameter the faster the conduction as there’s more ion channels so more sodium can get in
How does myelin affect speed of conduction of nervous impulses ?
Acts as an electrical insulator meaning less ATP is needed to transfer action potentials along an axon, dramatically increases speed of propagation
What is the function of a synapse ?
Junction between neurones
Send nervous impulses between neurones in 1 direction
What are the 2 types of synapses ?
Electrical and chemical
What is an electrical synapse features ?
Directly transmits impulse from 1 neurone to the next
What are the features of a chemical synapse ?
Impulse is transmitted by a neurotransmitter
Chemical is secreted by exocytosis into pre synaptic membrane in response to an action potential
Diffuses across synaptic cleft
Binds to receptors on post synaptic membrane
What does an action potential cause in synaptic transmission ?
Voltage gated calcium channels to open
How is the sodium channel opened in synaptic transmission ?
Receptor protein changes shape on binding making the channel open
What causes a wave of depolarisation to be sent along the membrane in synaptic transmission ?
NA+ ions diffusing into post synaptic membrane
What causes the post synaptic membrane to depolarise in synaptic transmission ?
Threshold being reached
What is acetylcholine broken down by ?
Acetylcholinesterase
What is acetylcholine broken down into ?
Acetate and choline
What happens if acetylcholine remains in the synaptic cleft ?
Continuous initiation of impulses and a potential merging of impulses
What are drugs ?
A medicine or other substance which has a psychological affect when ingested or introduced into the body
What do drugs affect ?
The actions of neurotransmitters and inhibit breakdown of a neurotransmitter
Name 4 types of drugs ?
Organophosphates
Sedatives
Stimulants
Psychoactive drugs
What are the effects of sedatives on the nervous system ?
Inhibit
Create fewer action potentials in the post synaptic neurone
Name a type of sedative
Alcohol
What are the affects of stimulants on the nervous system ?
Cause more action potentials in the post synaptic membrane
Name a type of stimulant
Amphetamines
How do organophosphates affect synapses ?
Prevent breakdown of acetylcholine so it isn’t hydrolysed and remains in the synaptic cleft meaning the post synaptic neurone repeatedly fires
Name 3 organophosphates
Insecticides
Herbicides
Nerve gases
What are psychoactive drugs?
Drugs that act on the central nervous system affecting various neurotransmitters and their receptors
What are the 2 types of psychoactive drugs ?
Recreation and medicinal
Name 3 medicinal psychoactive drugs
Ritalin
Prozac
Paxil
Name 3 recreational psychoactive drugs
Cocaine
Nicotine
Alcohol
What are the effects of nicotine on the body ?
Mimics the action of the neurotransmitter and binds to receptors on the post synaptic membrane
How does caffeine work as a stimulant ?
Increases metabolic rate in pre synaptic cells so ATP synthesis increases which causes neurotransmitter synthesis to also increase