3.7 homeostasis Flashcards
Homeostasis?
maintaining a constant internal environment
Negative feedback?
a change in a system produces a second change reverses the first change, back to a set point
Negative feed back mechanism?
Receptor detects level of a factor and deviation from set point
Detects change and sends instructiions to a co-ordinator which communicates with an effector i.e muscle or gland
Effector makes corrective response, retuning factor to set point
Examples of negative feedback
Glucose concentration in plasma, if above set point, insulin is secreted from pancreas, converting to glycogen, and increasing the rate of glucose respiration
If below set point glucagon secreted which converts glycogen to glucose
If body temp below set point, increased respiration generates more heat and blood vessels constrict to retain heat
Positive feedback?
an effector increases a change further away from the set point
Examples of positive feedback
Oxytocin stimulates uterus contractions at end of pregnancy
Aggregation of platelets - at first stage of clot formation - secrete signalling molecules to attract more molecules
4 places of excretion
Lungs - (Carbon dioxide, water in expired air)
Kidneys - (urea, uric acid, creatinine in urine)
Skin(urea) in sweat
Liver( bile pigments) in faeces
How is water removed from the body?
secreted in tears and saliva
egested in faeces
Metabolic waste product of respiration in expired air
2 functions of kidney and definitions
Excretion - removal of nitrogenous metabolic waste made by the body
Osmoregulation - control of the water potential of the body fluids ( plasma, tissue, fluid, lymph) by regulating water content, and therefore the solute potential
Production of Urea
Proteins hydrolysed to amino acids
Excess amino acids deaminated in the liver and the ammonia group is converted to urea
Amino acids > Alpha Keto Acid + Ammonia >Urea
Kidney coated in?
Tough renal capsule
Structure of Kidney?
Blood from renal artery filtered in the cortex from the glomerulus into Bowman’s Capsule
Medulla contains loop of Henle