3.7 Cell Cycle Flashcards
Motor proteins use ___ to power transport along the microtubule “railroad”
ATP
ATP binding makes actin ___ more easily at the ___ end
polymerize
+ end
___ enables cytokines
Contractile ring formation of overlapping actin and myosin filaments
ATPase activity increeases once bound in ___
Filaments
Myosin moves what?
Membranes or cell components
Muscle is contracted by
Actin and myosin
Most important cell cycle checkpoints:
Enter S phase
Enter Mitosis
Describe “enter S phase” check point
Is the environment favorable?
Is it ready to replicate?
Describe the “enter Mitosis” phase
Is all DNA replicated?
Is environment favorable?
Phosphorylation allows ___ signals to control ___ protein activity
Extracellular
Intracellular
Reversible covalent modifications turn proteins on, off, or both? What can do this?
Both
Kinase and phosphatase
Extracellular signals can control intracellular protein activity by activating ___ activators or ___
Allosteric activators or inhibitors
The cell cycle is controlled by ___
Cdk
Function of Cdk. How does it become active?
- Cdk phosphorylates cell targets that enter different parts of cell cycle
- Requires cyclin binding to form Cdk complexes (it allosterically binds)
How does Cdk become fully active?
Cdk-activating kinase (CAK) phosphorylates Cdk