343 exam 2 meds Flashcards
What does digitalis (digoxin) do?
- increases myocardial contractility -> more forceful contractions of the heart
- decreases HR and improves cardiac output
- increases coronary artery blood flow
- increases urine production
- helps with edema, exertional and paroxysmal nocturnal dyspnea, cough, and cyanosis
- decreases preload and increases stroke volume
what are side effects/adverse effects of digoxin?
- bradycardia
- dysrhythmias
- anorexia**
- N/V**
- diarrhea**
- headache
- dizziness
- blurred or yellow/green vision**
- halos around lights**
- confusion
- weakness
what are signs of digitalis/digoxin toxicity?
- anorexia
- N/V
- diarrhea
- blurred vision
- yellow/green vision
- halos around lights
what is the antidote for digitalis toxicity?
digoxin immune fab
what are some contraindications for digoxin?
- HR below 60
- signs of digitalis toxicity
- digoxin level >2 ng/mL (toxicity)
what patient education will the nurse provide to a patient taking digoxin?
teach the patient how to check pulse daily (before taking digoxin) and report side effects
what will the nurse monitor for in a patient taking digoxin?
- peripheral/pulmonary edema
- HR
- serum digoxin level
- serum K+ level (for hypokalemia)
what does milrinone lactate do?
- promotes stronger heart beat
- increases stroke volume and cardiac output
- vasodilation
- used as a “last resort” medication
administer IV milrinone lactate no longer than __ to __ hours to avoid severe cardiac dysrhythmias
48 to 72 hours
what are some adverse effects of milrinone lactate?
- dysrhythmias
- hypotension
- angina
- hypokalemia
- tremors
- thrombocytopenia (decreased platelets)
what do nitrates do?
- promote vasodilation
- decrease preload and afterload
what are some side effects/adverse effects of nitrates?
- headache
- hypotension**
- flushing
- dizziness
- weakness
-syncope
what patient education does the nurse provide to a patient taking a nitrate (such as nitroglycerin)?
- do not abruptly discontinue (if taking continuously)
- if using transdermal patch, allow a nitrate-free period at bedtime
- burning sensation with nitroglycerin indicates the drug is still potent
- never chew or swallow sublingual nitroglycerin
- lie down if nitroglycerin is needed**
- can take up to 3 tablets 5 minutes apart. call 911 if second tablet is taken
- teach pt proper application of nitrate topical ointments/transdermal forms (site rotation, removal of old medication, etc.)
- teach pt how to check their own pulse
what patient education will the nurse provide to a patient taking anti-dysrhythmics (such as beta-adrenergic blockers)?
- tell pt to report side effects/adverse reactions
- advise pt to avoid alcohol, caffeine, and tobacco
what do diuretic drugs generally do?
- accelerate rate of urine formation
- removes sodium and water
- used to treat HTN, HF, edema, and renal failure
if a patient loses 2.2 lbs, how much fluid has the patient lost?
1 L
what is a contraindication for diuretics?
- gout or renal stones (it can increase uric acid levels)
- renal failure
what should the nurse monitor in a patient taking diuretics?
- daily weights
- fluid/electrolyte balance (especially hyponatremia)
- urine output
- check peripheral extremities for edema
what do thiazide and thiazide-like diuretics do?
- promote sodium, chloride, and water excretion
- first-line treatment for HTN
- treats peripheral edema
- acts on distal convoluted renal tubule
what are some side effects/adverse reactions of thiazide and thiazide-like diuretics?
- sodium and K+ LOSS**
- elevated calcium, lipids, uric acid**
- dizziness, headache, hypotension, urticaria
- GI distress, constipation, hyperglycemia**
what patient education will the nurse provide to a patient taking a thiazide diuretic?
- suggest that the patient take the drug early in the morning to avoid sleep disturbance from nocturia
- instruct patient to slowly change positions from lying to standing
what is the most important electrolyte for the nurse to monitor in a patient taking a loop diuretic or thiazide diuretic?
potassium (for hypokalemia)
what does a loop diuretic do?
- excrete sodium, water, potassium, calcium, magnesium
- acts on the ascending loop of Henle
what are some side effects/adverse reactions of loop diuretics?
- hypokalemia**
- elevated glucose and uric acid
- dehydration
- photosensitivity
- tinnitus**
- blurred vision
- rash
- can be neurotoxic and nephrotoxic
how can loop diuretics put a patient at increased risk for digoxin toxicity?
if the patient has hypokalemia, it can increase the effects of digoxin, leading to toxicity
what will the nurse monitor in a patient taking a loop diuretic?
- check electrolytes/fluid balance
- check potassium**
- fluid intake (to prevent dehydration)
- monitor for dysrhythmias in people taking digoxin
- fall precautions if appropriate
what patient teaching will the nurse provide to a patient taking a loop diuretic?
- instruct patient to slowly change positions from lying to standing
- encourage addition of high potassium foods or potassium supplements
- suggest that the patient take the drug early in the morning to avoid sleep disturbance from nocturia
what do osmotic diuretics do?
- increase sodium reabsorption in the proximal tubule and the loop of henle
- excrete sodium, chloride, potassium, water
- used to excrete toxic substances
- decreases ICP and IOP
- causes rapid diuresis
what are some side effects/adverse reactions to osmotic diuretics?
- blurred vision
- fluid and electrolyte imbalances**
- GI distress
- acidosis
- pulmonary edema
- tachycardia
what are some contraindications for osmotic diuretics?
- heart disease
- HF
- renal failure
what do carbonic anhydrase inhibitors do?
- excrete sodium, potassium, and bicarbonate
- block action of enzyme carbonic anhydrase
- decrease IOP in patients with open-angle glaucoma
what are some side effects of carbonic anhydrase inhibitors?
- confusion
- orthostatic hypotension
- GI distress
- metabolic acidosis
- fluid/electrolyte imbalance
- crystalluria
- renal calculi
- hemolytic anemia
what do potassium-sparing diuretics (aldosterone inhibiting diuretics) do?
- promote sodium/water excretion and potassium retention
- blocks action of aldosterone at the receptor
- used for edema from HR, cirrhosis of liver
what are some side effects/adverse reactions to potassium-sparing diuretics?
- photosensitivity
- dizziness
- headache
- weakness
- GI distress
- paresthesia
- hyperkalemia
- hyperuricemia
- muscle cramps
what should the nurse monitor in a patient taking potassium-sparing diuretics?
- urinary output
- vital signs
- hyperkalemia
what patient education will the nurse provide to a patient taking potassium-sparing diuretics?
- take in the morning to avoid nocturia
- advise patients with high serum potassium levels to avoid foods high in potassium
what do beta-adrenergic blockers generally do?
- decrease HR and BP
- decrease force of contraction
- decrease rate of AV conduction
what do beta blockers usually end in?
-olol
what is the difference between nonselective and cardioselective beta blockers?
nonselective: inhibits beta1 and beta2 receptors (affects the heart and lungs)
cardioselective: inhibits beta1 receptors (affects only the heart)
what are the side effects of beta blockers?
- hypotension
- bradycardia
- dizziness
- insomnia
- nightmares
- fatigue
- depression
- ED**
- bronchospasm**
- wheezing **
- abnormal blood glucose**
which patients should nurses be careful with when administering nonselective beta blockers?
- diabetics
- respiratory related issue patients (asthma, COPD, etc)
what should the nurse monitor for before administering a beta blocker?
pulse
signs of CHF or hypotension
what patient education can the nurse provide to a patient taking a beta blocker?
- teach patient to take their pulse
- fatigue will improve with time
- discuss bradycardia
- possible sexual dysfunction
- need to regularly monitor lipid levels
- educate patients to not stop taking suddenly**
what do centrally acting alpha2 agonists do?
- stimulate alpha2 receptors
- decrease cardiac output
- decrease epinephrine, norepinephrine, and renin release
- increases vagus activity
what is a contraindication for centrally acting alpha2 agonists?
impaired liver function
what are some side effects of centrally acting alpha2 agonists?
- significant dizziness
- drowsiness
- dry mouth
- headache
- peripheral edema
- bradycardia
what patient teaching will the nurse provide to a patient taking a centrally acting alpha2 agonist?
- do not abruptly stop taking the drug. rebound hypertension may result
what do alpha-adrenergic blockers do?
- block the alpha-adrenergic receptors
- result in vasodilation and decreased blood pressure
- relaxes smooth muscle of the prostate and bladder neck- good choice for males with BPH
what are some side effects of alpha-adrenergic blockers?
- orthostatic hypotension**
- first dose syncope and hypotension
- tachycardia
- headache
- drowsiness
- dizziness
- nausea
- nasal congestion
- edema**
- weight gain**