[3.3.7] Optical Isomerism

Question 1

What is stereoisomerism?

Answer 1

Question 2

How does optical isomerism occur?

Answer 2

Question 3

What is the term that refers to a carbon atom that has 4 different groups attached to it?

Answer 3

Question 4

Two compounds that are optical isomers of each other are called…?

Answer 4

Question 5

What is a mixture containing a 50/50 mixture of enantiomers known as?

Answer 5

Question 6

Draw the optical isomers of butan-2-ol.

Answer 6

Question 7

What efffect do optical isomers have on plane-polarised light?

Answer 7

Question 8

What effect does a racemic mixture have on plane-polarised light?

Answer 8

Question 9

How does a racemate form?

Answer 9

Question 10

What two mechanisms can result in the formation of a racemate?

Answer 10

Question 11

Draw the nucleophilic addition of HCN to butanone to show the formation of a racemate.

Answer 11

Question 12

Draw the electrophilic addition of HBr to butan-1-ene to show the formation of a racemate.

Answer 12

Question 13

Drug action may be determined by the stereochemistry of the molecule. Different optical isomers may have different effects. Give an example of this.

Answer 13