[3.3.11] Amines Flashcards
Preparation, Base Properties & Nucleophilic Properties.,
How do you name amines?
Name these two molecules.
Name these three molecules.
Name this molecule.
Describe the base strength of primary aliphatic amines.
Explain the difference in base strength of primary aliphatic amines compared to ammonia.
Describe the base strength of secondary aliphatic amines.
Explain the difference in base strength between secondary aliphatic amines and primary aliphatic amines.
Describe the base strength of aromatic amines.
Explain the difference in base strength of aromatic amines compared to aliphatic amines.
What is the overall order of base strength of amines?
When amines react with acids, what product is formed?
Write an equation for the reaction between methylamine and hydrochloric acid.
What can you add to the product of this reaction to convert it back to the amine?
Write equations for the reactions between:
- Methylamine and H+
- Diethylamine and H+
- Triethylamine and H+
(The H+ coming from an acid)
How do you make a basic buffer solution from an amine?
Describe and explain the issue in forming a primary amine by the reaction of ammonia with a halogenoalkane.
What solution is there to this issue?
How can primary amines be formed and through what mechanism are they formed?
- Primary amines can be formed by the nucleophilic substitution reaction between halogenoalkanes and ammonia in a one-step reaction.
STEP 1
Write the overall equation for the reaction between ammonia and bromoethane.
Draw the mechanism for this reaction.
STEP 2
Draw the mechanism for the reaction between the product produced in step 1 and bromoethane.
What type of product is produced, name it.
STEP 3
Draw the mechanism for the reaction between the product produced in step 2 and bromoethane.
What type of product is produced, name it.
STEP 4
Draw the mechanism for the reaction between the product produced in step 3 and bromoethane.
What type of product is produced, name it.
If you used an excess of halogenoalkane with ammonia, what would predominately be produced?
Draw a diagram to represent the overall scheme of reactions that occur when a halogenoalkane reacts with ammonia.
Use “RX” to represent the halogenoalkane.
What can quaternary ammonium salts be used as?
Why can they be utilised like this?
Draw the structure of all the products formed when bromomethane reacts with propylamine.
Name all the products
Describe how you can prepare amines from nitriles.
What are the advantages and disadvantages of this?
Using bromoethane as a starting product, write equations to show how you can form a primary amine by reacting bromoethane with a nitrile.
Describe the reagent, conditions and mechanism to form aromatic amines from nitroarenes.
Draw the overall equation for this reaction where the nitroarene is nitrobenzene.
What is the change in the functional group, reagents and conditions when ethanoyl chloride reacts with methylamine?
Draw the structural and displayed formulae for this reaction.
What is the change in the functional group, reagents and conditions when ethanoic anhydride reacts with methylamine?
Draw the structural and displayed formulae for this reaction.
