33. Renal fibrosis; chronic renal diseases

Question 1

Renal fibrosis process

Answer 1

replacement of normal parenchyma with collagen fibrous CT

Question 2

regeneration of nephrons in Renal fibrosis

Answer 2

not possible

Question 3

Renal fibrosis results after

Answer 3

• infarction
• glomerulonephritis
• tubulointerstitial disease
• chronic pelic disease

(loss of working parenchyma)

Question 4

what does ‘end stage kidney’ mean?

Answer 4

renal fibrosis turns into it, irreparable damage

common change to all regressive change

Question 5

which regressive change can lead to ‘end stage kidney’

Answer 5

• interstitial fibrosis
• tubular atrophy
• oxalate crystals
• glomerular atrophy

Question 6

chronic renal disease

Answer 6

• is progressive
• loss of nephrons & severe scarring
• kidney can’t concentrate urine
• decrease prod of EPO

(leads to anaemia)

Question 7

concequence of chronic renal disease

Answer 7

• Azotaemia
• uraemia

(hypertension)

Question 8

electrolyte manifestation of chronic renal disease

Answer 8

dehydration, edema, hyperkalaemia, met. acidosis

Question 9

Ca & P manifestation of chronic renal disease

Answer 9

• hyper P
• hypo Ca
• 2ndary hyperparathydoidism
• systemic calcification

Question 10

haematologic manifestation of chronic renal disease

Answer 10

anemia

Question 11

cardiopulmonary manifestation of chronic renal disease

Answer 11

• hypertension
• congestive heart failure
• uremic pericarditis

Question 12

gastrointestinal manifestation of chronic renal disease

Answer 12

nausea & vomiting
bleeding
stomatitis
oesophagitis

smelly breath & ulceration of the ventral part of the tongue