3.3 Flashcards
Is there acute infarction in TIA
nope
therapy for noncardiogenic stroke/tia
clopidogrel
aspirin
therapy for cardiogenic stroke/tia
warfarin or direct oral anticoagulant
meningiomas arise from what cells
arachnoid cap cells
where are meningiomas commonly found
base of skull
perivenous sinuses
what is the second leading cause of death worldwide
stroke
when do embolic strokes typically occur
during day
when do thrombotic strokes typically occur
at night
subdural hemorrhage is due to
bridging veins
who is at risk for subdural hematoma
elderly
alcoholics
are neurologic symptoms gradual or sudden in subdural hematoma
gradual
can the bleed cross the suture line in subdural hematoma
YES
what reflex do we commonly see in epidural hematoma
Cushing reflex
what is Cushing reflex
triad of HTN, bradycardia, irregular breathing
in which hematoma type does the bleed appear to be biconvex
epidural hematoma
in which hematoma subtype do people experience a thunderclap headache
subarachnoid
AVM increases risk of
subarachnoid hematoma
what might you see on LP for subarachnoid hematoma
xanthochromia
what is a mycotic aneurysm due to
bacteria
what is typically a secondary phenomenon from subarachnoid hemorrhage
intraventricular hemorrhage
what brain tumor is most commonly found in kids
astrocytoma
what brain tumor is most commonly found in adults
glioblastoma
what is the most aggressive brain tumor
glioblastoma
what 2 viruses increase risk of glioblastoma
HHV-6
cytomegalovirus
what do we call a glioblastoma that crosses the corpus callosum
butterfly glioma
what virus is positive in 90% of cases of CNS lymphoma
Epstein-Barr virus
myasthenia gravis is an autoimmune disorder in which one develops antibodies to
acetylcholine
in what population of people is myasthenia gravis more common
young women
older men
what type of hypersensitivity reaction is myasthenia gravis
type 2
myasthenia gravis has a strong association with
abnormal thymus gland
what are the two main manifestations of myasthenia gravis
ocular weakness
generalized weakness worsened with repeated use
what are typically the PRESENTING symptoms (first symptoms) of myasthenia gravis
diplopia
ptosis
what is spared in myasthenia gravis
pupils
when does muscle weakness worsen in myasthenia gravis (this is so important)
with activity – worsens throughout the day
when does muscle weakness worsen in myasthenia gravis (this is so important)
with activity – worsens throughout the day
what is typically preserved in myasthenia gravis besides pupils
sensation
deep tendon reflexes
what should be done in all patients with myasthenia gravis to detect thymus gland abnormalities
chest imaging
what test can be performed in myasthenia gravis
ice pack test
what two tests are more accurate for myasthenia gravis
repetitive nerve stimulation (RNS)
single fiber electromyography (SFEMG)
block in CSF pathway
obstructive hydrocephalus
impaired absorption of CSF
communicating hydrocephalus
triad of normal pressure hydrocephalus
gait disturbance (wobbly)
urinary incontinence (wet)
cognitive dysfunction/dementia (wacky)
what type of gait do people with normal pressure hydrocephalus typically have
wide-based shuffling gait –> magnetic gait!!!!
treatment for normal pressure hydrocephalus
ventriculoperitoneal shunt
Skull has a set volume and pressure for what 3 things
brain volume
CSF
intracranial venous and arterial blood
localized collection of pus in the parenchyma of the brain
brain abscess
important risk factor for brain abscess
immunocompromised
which lobes are most likely to be affected in brain abscess
frontal
temporal
which type of glaucoma is an emergency
ACUTE NARROW angle closure glaucoma
which type of glaucoma is painful
acute narrow angle closure glaucoma
are people who are farsighted or near-sighted at increased risk of developing acute narrow angle closure glaucoma
farsighted (hyperopes)
is eye pain unilateral or bilateral in acute narrow angle closure glaucoma
unilateral
what type of vision do people with acute narrow angle closure glaucoma typically have
tunnel vision (halos around lights and peripheral vision)
what will you see on fundoscopy for acute narrow angle closure glaucoma
optic disc cupping or blurring of optic nerve
on tonometry, what would you expect for the pressure in acute narrow angle closure glaucoma
> 21 mmHg
do you see hypotension or hypertension in AAA
hypotension
is chronic open angle glaucoma painless or painful
painless
what is papilledema
optic nerve swelling
acute inflammatory demyelination of the optic nerve
optic neuritis
what is the most common cause of optic neuritis
multiple sclerosis
what medication is a common cause of optic neuritis
ethambutol
is optic neuritis painful or painless
painful
because multiple sclerosis is a common cause of optic neuritis, what might we see in regards to the pupil
Marcus gunn pupil
brodman area for Wernicke
brodman 22
what lobe is affected in wernickes aphasia
temporal
what lobe is affected in Broca’s aphasia
frontal
brodmann areas or Broca’s aphasia
44 and 45
what disease are AVMs commonly associated with
Osler-Weber-Rendu disease
what lobes are affected in posterior reversible encephalopathy syndrome
posterior occipital parietal lobes
how does PRES commonly present
seizure
is the headache in PRES responsive to therapy
no
when do you perform carotid endarterectomy
70-99% stenosed
what nerve is affected in Bell’s palsy
facial nerve/CN7
what virus is the most common cause of Bell’s palsy
HSV1
eye on the affected side moves laterally and superiorly when eye closure is attempted
Bell phenomenon seen in Bell’s palsy