3.2 Flashcards
what is a closed circulation system?
blood travels through blood vessels with the impetus being generated by a muscular pump or heart
what is an open circulation system?
‘blood’ bathes all the cells and organs of the body
what are the technical names for ‘blood’ and others in the process?
the blood called haemolymph and is in the body cavity called haemocoel
what are facts about closed circulation?
delivers blood quickly to tissues under pressure
what is single circulation?
blood passes through heart once in each circulation
what is the heart like in a fish?
single circulation. heart has two chambers (atrium and ventricle)
what is a disadvantage of single circulation?
blood loses pressure around the circuit resulting in slower circulation
what is a double circulation system?
blood passes through the heart twice in one circulation of the system
what is an advantage of a double circulation system?
blood is depressurised when it leaves the gas exchange surface giving a faster and more efficient circulation to the tissues
what type of circulation system to insects have?
open
what type of circulation system do earthworms have?
closed
what type of circulation do mammals have?
closed, double
why is blood returned to the heart in mammals?
blood pressure is reduced in capillaries of lungs and would be too low to reach whole body
what is the route of blood in one circulation?
1- (superior or inferior) vena cava
2- right atrium
3- tricuspid valve
4- right ventricle
5- pulmonary artery
6- lungs
7- pulmonary vein
8- left atrium
9- bicuspid value
10- left ventricle
11- aorta
12- body
what type of blood is on the right side of the heart?
deoxygenated
what type of blood is on the left side of the heart?
oxygenated
what are the stages in the cardiac cycle?
1- cardiac diastole
2- atrial systole, ventricular diastole
3- atrial diastole, ventricular systole
what happens during cardiac diastole?
blood at low pressure flows into the atria which increases the pressure, some of blood flows through tri/bicuspid valves and into relaxed ventricles
what happens in atrial systole and ventricular diastole?
when atria are full their walls contract cause blood to be pushed into ventricles, pressure in atria is increased when it contracts, pressure in ventricles increases as it fills with blood
what happens during atrial diastole and ventricular systole?
after a short delay the ventricles contract from apex up which increases pressure, due to higher pressure in ventricles than atria the blood pushes back on valves causing them to shut, semi lunar valves open and blood leaves heart, ventricles relax and semi lunar valves shut (blood falls back down a bit due to gravity)
what causes the sound of the heart beat?
valves closing
what are periods of contracting called?
systole
what are periods of relaxing called?
diastole
what does one cardiac cycle consist of?
atria and ventricles contracting so that the blood that has entered the heart is pumped out
how many times a minute does the cardiac cycle occur?
60-80 times every minute
what is the structure of blood vessels?
tunica intima, tunica media, tunica externa
what is the tunica intima?
single layer of endothelium, smooth lining to reduce friction, some arteries are supported by elastin-rich collagen
what is the tunica media,?
contains elastic fibres and smooth muscle
how is a pulse felt?
in arteries as elastic fibres recoil and push blood through
what does contraction of the muscles do in blood vessels?
regulates blood flow and maintains blood pressure when transported further from heart
what is the tunica externa?
contains collagen fibres which resist over stretching
how big are arteries?
10mm
how big are capillaries?
0.2mm
how big are veins?
6mm
what is the function of arteries?
carry blood away from heart, thick muscular walls withstand bloods high pressure, branch into arterioles then into capillaries
what is the function of capillaries?
vast network that penetrates all tissues and organs, blood from capillaries collect into venues into veins
what is the function of veins?
transport blood from body to heart, larger lumen and thinner walls and lower flow rate and blood pressure, veins above heart move by gravity, moves through other veins by pressure from surrounding muscle, have semi-lunar valves to prevent backflow, faulty functioning can contribute to varicose veins and heart failure
why are there pores between cells in capillaries?
to be permeable to water and solutes for exchange between tissues and blood
why are there many capillaries in a capillary bed?
to decrease blood flow for more time for materials to exchange
what type of muscle is in the heart?
cardiac muscle
why is the heart myogenic?
its contracting is initiated from within the heart itself and not from nervous stimulation
where does the signal for the heart contracting come from?
sinoatrial node
describe how heartbeat is controlled
the sinoatrial node starts the wave of depolarisation which results in contraction of atria when the waves spread out over the walls. there is a band of fibres which have electrical resistance so the waves cant spread past here. the atrioventricular node is located in the septum and can conduct so it will pass on the wave of depolarisation after a short gap. the excitation passes down the Bundle of His and to the Purkinje in the inner ventricular septum. it passes to the apex of the heart then through ventricular walls leading to them contracting from the apex up to make sure blood is pushed up and out.
what is haemoglobin made of?
4 globular proteins and 1 iron ion in each globular protein
what is haemoglobin?
the molecule that allows erythrocytes to carry oxygen and has an affinity for oxygen
what does affinity for oxygen mean?
it can carry oxygen molecules
what is hameoglobin called when oxygenated?
oxyhaemoglobin
what are the adaptations of red blood cells?
biconcave shape to maximise surface area for gas exchange, small and flexible to pass through narrow capillaries, no nucleus for more room to carry respiratory gases, packed with haemoglobin
what is the word equation for the reversible reaction of oxygen and haemoglobin?
haemoglobin + oxygen <> oxyhaemoglobin
what is the shorthand for haemoglobin?
Hb
what is the equation for the reversible reaction between oxygen and haemoglobin?
Hb + 4O2 <> Hb.4O2
how is oxygen transported from lungs to respiring tissue?
in the lungs oxygen diffuses into blood plasma and then down a concentration gradient into the erythrocyte. oxygen binds to haemoglobin to maintain concentration gradient. oxygen binds to the Fe2+ group. in respiring tissue the oxygen dissociates from oxyhaemoglobin and then oxygen can diffuse out of erythrocyte and to respiring cells
what is 100% saturation?
the haemoglobin is carrying its maximum amount of oxygen
what are the units for saturation?
SaO2 %
what is the normal saturation of blood leaving the lungs?
95-99%
what is concentration of oxygen referred to as? + units
partial pressure for oxygen (pO2) which is measured in kPa
why is ventilation important?
to allow lung tissue to have a high pO2